6-Methylquinoxaline

Base Information

• Chemical Name: 6-Methylquinoxaline
• CAS No.: 6344-72-5
• Molecular Formula: C9H8N2
• Molecular Weight: 144.176
• Hs Code.: 2933990090
• Mol file: 6344-72-5.mol

Synonyms:Quinoxaline, 6-methyl-;NSC 51327;6-Methylquinoxaline 99%;

Chemical Property of 6-Methylquinoxaline

Chemical Property:

• Vapor Pressure: 0.0237mmHg at 25°C
• Melting Point: 218.5°C
• Refractive Index: 1.6190
• Boiling Point: 257.2ºC at 760 mmHg
• PKA: 1.40±0.30(Predicted)
• Flash Point: 108.8ºC
• PSA: 25.78000
• Density: 1.141 g/cm³
• LogP: 1.93820
• Storage Temp.: Sealed in dry,Room Temperature

Purity/Quality:

97% ^*data from raw suppliers

6-Methylquinoxaline ^*data from reagent suppliers

Safty Information:

• Pictogram(s): XnXiCF
• Hazard Codes: Xn,Xi,C,F
• Statements: 22-36/37/38-34-11
• Safety Statements: 23-26-36/37/39-45-16

MSDS Files:

SDS file from LookChem

Useful:

• Uses: 6-Methylquinoxaline (CAS# 6344-72-5) can be used as a conductive roller for electrophotographic apparatus. It has also be known for its sequential synthesis, olfactory properties, and biological activity.

Technology Process of 6-Methylquinoxaline

There total 15 articles about 6-Methylquinoxaline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

Glyoxal (131543-46-9,107-22-2) + 4-methyl-1,2-diaminobenzene (496-72-0) → 6-methylquinoxaline (6344-72-5)

Guidance literature:

With 10 wtpercent sulfated polyborate; In neat (no solvent); at 100 ℃; for 0.05h; Green chemistry;

DOI:10.1007/s12039-017-1235-0

Reference yield: 93.0%

6-methyl-1,2,3,4-tetrahydro-quinoxaline (6639-93-6) → 6-methylquinoxaline (6344-72-5)

Guidance literature:

With potassium tert-butylate; In o-xylene; at 140 ℃; for 36h; Inert atmosphere;

DOI:10.1002/adsc.201900499

Reference yield: 87.0%

ethanolamine (141-43-5) + 4-methyl-1,2-diaminobenzene (496-72-0) → 6-methylquinoxaline (6344-72-5)

Guidance literature:

With cesiumhydroxide monohydrate; [(η⁶-p-cymene)₂Ru₂(2,7-bis(di-2-pyridinyl)-1,8-naphthyridine)Cl₂](PF₆)₂; oxygen; at 120 ℃; for 23h; Inert atmosphere; Molecular sieve;

DOI:10.1016/j.jorganchem.2014.10.028

upstream raw materials:

Glyoxal

4-methyl-1,2-diaminobenzene

glyoxal sodium bisulfite

1-phenyl-5-p-tolyl-1,2,5-triazapentadiene

Downstream raw materials:

(5Z)-5-(6-quinoxalinylmethylidene)-2-[(2,4,6-trichlorophenyl)amino]-1,3-thiazol-4(5H)-one

1,1-dimethylethyl {2-[(4-chloro-3-{[(5Z)-4-oxo-5-(6-quinoxalinylmethylidene)-4,5-dihydro-1,3-thiazol-2-yl]amino}phenyl)amino]-1,1-dimethyl-2-oxoethyl}carbamate

N-(2-chloro-3-{[(5Z)-4-oxo-5-(6-quinoxalinylmethylidene)-4,5-dihydro-1,3-thiazol-2-yl]amino}phenyl)cyclobutanecarboxamide

N-(2-chloro-3-{[(5Z)-4-oxo-5-(6-quinoxalinylmethylidene)-4,5-dihydro-1,3-thiazol-2-yl]amino}phenyl)benzamide