N,N'-2-Phenylenedimaleimide

Base Information

• Chemical Name: N,N'-2-Phenylenedimaleimide
• CAS No.: 13118-04-2
• Molecular Formula: C14H8 N2 O4
• Molecular Weight: 268.229
• European Community (EC) Number: 236-046-5
• NSC Number: 13693
• UNII: W46FEU5446
• DSSTox Substance ID: DTXSID00156935
• Nikkaji Number: J263A
• Wikidata: Q27292281
• ChEMBL ID: CHEMBL1734763
• Mol file: 13118-04-2.mol

Synonyms:N,N'-2-phenylenedimaleimide;N,N'-2-phenylenedimaleimide homopolymer;N,N'-o-phenylenedimaleimide;o-phenylene bismaleimide

Chemical Property of N,N'-2-Phenylenedimaleimide

Chemical Property:

• Melting Point: 245-247 °C (dec.)(lit.)
• Refractive Index: 1.5910 (estimate)
• Boiling Point: 459.7°Cat760mmHg
• PKA: -1.08±0.20(Predicted)
• Flash Point: 223.7°C
• PSA: 74.76000
• Density: 1.567g/cm³
• LogP: 0.67540
• Storage Temp.: Poison room
• Solubility.: Warm Acetone, Warm Acetonitrile, Warm DMSO
• XLogP3: 0.2
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 2
• Exact Mass: 268.04840674
• Heavy Atom Count: 20
• Complexity: 478

Purity/Quality:

97% ^*data from raw suppliers

1,2-Phenylene-bis-maleimide ^*data from reagent suppliers

Safty Information:

• Hazard Codes: T+
• Statements: 36/37/38-26-22
• Safety Statements: 22-24/25

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Canonical SMILES: C1=CC=C(C(=C1)N2C(=O)C=CC2=O)N3C(=O)C=CC3=O
• Uses: A short, sulfhydryl reactive homobifunctional crosslinking reagent for protein crosslinking. A short, sulfhydryl reactive hmombifunctional crosslinking reagent for protein crosslinking

Technology Process of N,N'-2-Phenylenedimaleimide

There total 2 articles about N,N'-2-Phenylenedimaleimide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

→ N,N'-(1,2-phenylene)bismaleimide (13118-04-2)

Guidance literature:

With sodium acetate; acetic anhydride;

DOI:10.1021/ja01592a020

Reference yield:

→ N,N'-(1,2-phenylene)bismaleimide (13118-04-2)

Guidance literature:

Reference yield: 71.0%

N,N'-(1,2-phenylene)bismaleimide (13118-04-2) + N,N-dibenzylhydroxylamine (621-07-8) → 1-[3-[(N,N-dibenzylamino)oxy]-2,5-dioxopyrrolidin-1-yl]-2-[2,5-dioxo-1H-pyrrol-1-yl]benzene (111363-50-9) + 1,2-bis[3-[(N,N-dibenzylamino)oxy]-2,5-dioxopyrrolidin-1-yl]benzene (111363-49-6)

Guidance literature:

In tetrahydrofuran; for 72h; Heating;

DOI:10.1021/jo00259a032

Downstream raw materials:

1,2-bis<3-(3,5-di-t-butyl-4-hydroxyphenylthio)-2,5-dioxopyrrolidin-1-yl>benzene

1-[3-[(N,N-dibenzylamino)oxy]-2,5-dioxopyrrolidin-1-yl]-2-[2,5-dioxo-1H-pyrrol-1-yl]benzene

1,2-bis[3-[(N,N-dibenzylamino)oxy]-2,5-dioxopyrrolidin-1-yl]benzene