N,N-Dibenzylhydroxylamine

Base Information

• Chemical Name: N,N-Dibenzylhydroxylamine
• CAS No.: 621-07-8
• Molecular Formula: C14H15NO
• Molecular Weight: 213.279
• Hs Code.: 2928000090
• European Community (EC) Number: 210-667-1
• NSC Number: 93968
• UNII: FWX35J4X22
• DSSTox Substance ID: DTXSID3044702
• Nikkaji Number: J79.755C
• Wikidata: Q72463623
• ChEMBL ID: CHEMBL449306
• Mol file: 621-07-8.mol

Synonyms:N,N-Dibenzylhydroxylamine;621-07-8;Dibenzylhydroxylamine;N,N-Dibenzylhydroxyamine;Benzenemethanamine, N-hydroxy-N-(phenylmethyl)-;Hydroxylamine, N,N-dibenzyl-;n,n-dibenzyl-hydroxylamine;N-Benzyl-N-hydroxy-1-phenylmethanamine;FWX35J4X22;DTXSID3044702;EINECS 210-667-1;NSC 93968;NSC-93968;bisbenzylhydroxylamine;NSC93968;MFCD00004772;N.N-dibenzylhydroxylamine;Maybridge3_004477;bis(4-ethylphenyl)diazene;Hydroxylamine,N-dibenzyl-;n,n-dibenzyl hydroxylamine;n,n-dibenzylhydroxyl-amine;N-HYDROXYDIBENZYLAMINE;UNII-FWX35J4X22;SCHEMBL39645;DIBENZYL HYDROXYL AMINE;CHEMBL449306;Hydroxylamine, N,N-dibenzyl-,;DTXCID1024702;GXELTROTKVKZBQ-UHFFFAOYSA-;N,N-Dibenzylhydroxylamine, 98%;HMS1443L11;N,N-bis(phenylmethyl)hydroxylamine;AMY25733;Tox21_302001;CCG-41682;AKOS000121407;CS-W014971;DS-6000;IDI1_015864;([Benzyl(hydroxy)amino]methyl)benzene #;NCGC00256220-01;CAS-621-07-8;D2004;FT-0629443;EN300-19057;O12002;A833585;N-HYDROXY-N-(PHENYLMETHYL)BENZENEMETHANAMINE;SR-01000631739-1

Chemical Property of N,N-Dibenzylhydroxylamine

Chemical Property:

• Appearance/Colour: White powder
• Vapor Pressure: 1.92E-06mmHg at 25°C
• Melting Point: 125-128 °C(lit.)
• Refractive Index: 1.615
• Boiling Point: 379.7 °C at 760 mmHg
• PKA: 13.19±0.69(Predicted)
• Flash Point: 200.4 °C
• PSA: 23.47000
• Density: 1.136 g/cm³
• LogP: 3.07800
• Storage Temp.: Inert atmosphere,Store in freezer, under -20°C
• Water Solubility.: Insoluble in water
• XLogP3: 2.8
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 4
• Exact Mass: 213.115364102
• Heavy Atom Count: 16
• Complexity: 163

Purity/Quality:

99% ^*data from raw suppliers

N,N-Dibenzylhydroxylamine ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi
• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-37/39

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Canonical SMILES: C1=CC=C(C=C1)CN(CC2=CC=CC=C2)O
• Uses: N,N-Dibenzylhydroxylamine, upon oxidation, yields N-benzyl-α-phenylnitrone, which can undergo cycloaddition reaction with suitable dipolarophiles. It can be used to synthesize N,N,O-trisubstituted hydroxylamines and arylamines.

Technology Process of N,N-Dibenzylhydroxylamine

There total 29 articles about N,N-Dibenzylhydroxylamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

dibenzylamine (103-49-1) → N,N-dibenzylhydroxylamine (621-07-8)

Guidance literature:

With 3,3-dimethyldioxirane; In acetone; at 0 ℃; for 0.25h;

Reference yield: 94.0%

N,N-bis(benzotriazol-1-ylmethyl)hydroxylamine (28539-14-2) + phenylmagnesium bromide → N,N-dibenzylhydroxylamine (621-07-8)

Guidance literature:

In tetrahydrofuran; diethyl ether; for 1h; Heating;

Reference yield: 92.0%

dibenzylamine (103-49-1) → N-Benzylidenebenzylamine N-oxide (3376-26-9) + N,N-dibenzylhydroxylamine (621-07-8)

Guidance literature:

With Cumene hydroperoxide; 4 A molecular sieve; PVDF-membrane containing chiral Ti(IV); In chloroform-d1; at 60 ℃;

DOI:10.1016/j.tetlet.2004.07.142

upstream raw materials:

diethyl ether

N,N-dibenzyl-O-benzoylhydroxylamine

sodium ethanolate

ethanol

Downstream raw materials:

N,N,O-tribenzylhydroxylamine

benzaldehyde

tribenzylamine

N-benzyl hydroxylalmine

Refernces

• 1、 Xu-Xu, Qing-Feng,Zhang, Xiao,You, Shu-Li. "Enantioselective Synthesis of 4-Aminotetrahydroquinolines via 1,2-Reductive Dearomatization of Quinolines and Copper(I) Hydride-Catalyzed Asymmetric Hydroamination". supporting information. p. 5357 - 5362. Retrieved 2019/09/06.
• 2、 Rajput, Surendra K.,Patel, Anita,Bapat, Kishor N.. "Synthesis and characterization of N-methyl and N-benzyl cinnamohydroxamic acids". . p. 885 - 887. Retrieved 2017/02/10.