isosalsoline

Base Information

• Chemical Name: isosalsoline
• CAS No.: 4593-97-9
• Molecular Formula: C11H15 N O2
• Molecular Weight: 193.246
• Hs Code.: 2933499090
• Mol file: 4593-97-9.mol

Synonyms:(?à)-Isosalsoline; Isosalsoline; NSC131726

Chemical Property of isosalsoline

Chemical Property:

• Vapor Pressure: 5.65E-05mmHg at 25°C
• Boiling Point: 336.7°Cat760mmHg
• Flash Point: 157.4°C
• PSA: 41.49000
• Density: 1.106g/cm³
• LogP: 1.93630

Purity/Quality:

98.5% ^*data from raw suppliers

1,2,3,4-TETRAHYDRO-7-HYDROXY-6-METHOXY-1-METHYLISOQUINOLINE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of isosalsoline

There total 7 articles about isosalsoline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

(+)-β-hydrastine hydrochloride (5936-28-7) → N-Nor-1-methylcorypalline (4593-97-9) + meconin (569-31-3) + N-methyl-6,7-methylenedioxy-1,2,3,4-tetrahydroisoquinoline (494-55-3) + 6-methoxy-1,2-dimethyl-1,2,3,4-tetrahydroisoquinolin-7-ol (19641-12-4)

Guidance literature:

With C_. ochotensis var. raddeana; In water; at 24 ℃; for 38h; Product distribution; C_. platycarpa or C_. ophiocarpa, other temp., other times;

DOI:10.1002/ardp.19873200805

Reference yield:

(-)-β-Narcotine hydrochloride → N-Nor-1-methylcorypalline (4593-97-9) + meconin (569-31-3) + hydrocotarnine (550-10-7) + 6-methoxy-1,2-dimethyl-1,2,3,4-tetrahydroisoquinolin-7-ol (19641-12-4)

Guidance literature:

With C_. ochotensis var. raddeana; In water; at 24 ℃; for 38h; Product distribution; C_. platycarpa or C_. ophiocarpa, other temp., other times;

DOI:10.1002/ardp.19873200805

Reference yield:

(-)-α-Narcotine hydrochloride (912-60-7) → N-Nor-1-methylcorypalline (4593-97-9) + meconin (569-31-3) + hydrocotarnine (550-10-7) + 6-methoxy-1,2-dimethyl-1,2,3,4-tetrahydroisoquinolin-7-ol (19641-12-4)

Guidance literature:

With C_. ochotensis var. raddeana; In water; at 24 ℃; for 36h; Product distribution; C_. platycarpa, other temp., other times;

DOI:10.1002/ardp.19873200805

upstream raw materials:

diazomethane

(+/-)-salsolinol

(+)-β-hydrastine hydrochloride

(-)-α-Narcotine hydrochloride

Refernces

• 1、 Iwasa,Kamigauchi,Takao. "Biotransformation of phthalideisoquinoline alkaloids by corydalis tissue cultures". . p. 693 - 697. Retrieved 2007/10/02.