1H-Benzimidazol-6-amine, 5-chloro-1-(1-methylethyl)-2-(4-methyl-1-piperazinyl)-

Base Information

Chemical Name:1H-Benzimidazol-6-amine, 5-chloro-1-(1-methylethyl)-2-(4-methyl-1-piperazinyl)-
CAS No.:148014-93-1
Molecular Formula:C₁₅H₂₂ClN₅
Molecular Weight:307.826
Hs Code.:
DSSTox Substance ID:DTXSID20163868
Nikkaji Number:J557.902C
Wikidata:Q83032855
Mol file:148014-93-1.mol

Synonyms:6-Amino-5-chloro-1-isopropyl-2-(4-methyl-1-piperazinyl)benzimidazole;148014-93-1;1H-Benzimidazol-6-amine, 5-chloro-1-(1-methylethyl)-2-(4-methyl-1-piperazinyl)-;5-Chloro-1-(1-methylethyl)-2-(4-methyl-1-piperazinyl)-1H-benzimidazol-6-amine;KB 6806;KB 6933;KB-6806;C15H22ClN5;SCHEMBL1023815;C15-H22-Cl-N5;DTXSID20163868;QEANRFDFBNUCJR-UHFFFAOYSA-N;LS-32544

Suppliers and Price of 1H-Benzimidazol-6-amine, 5-chloro-1-(1-methylethyl)-2-(4-methyl-1-piperazinyl)-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 1H-Benzimidazol-6-amine, 5-chloro-1-(1-methylethyl)-2-(4-methyl-1-piperazinyl)-

Chemical Property:

Vapor Pressure:8.03E-09mmHg at 25°C
Boiling Point:464.9°C at 760 mmHg
Flash Point:235°C
Density:1.34g/cm³
XLogP3:2.4
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:2
Exact Mass:307.1563734
Heavy Atom Count:21
Complexity:358

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C)N1C2=C(C=C(C(=C2)N)Cl)N=C1N3CCN(CC3)C

Technology Process of 1H-Benzimidazol-6-amine, 5-chloro-1-(1-methylethyl)-2-(4-methyl-1-piperazinyl)-

There total 9 articles about 1H-Benzimidazol-6-amine, 5-chloro-1-(1-methylethyl)-2-(4-methyl-1-piperazinyl)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 73.0%

: 148014-96-4
5-chloro-1-isopropyl-2-(4-methyl-1-piperazinyl)-6-nitrobenzimidazole

: 148014-93-1
6-amino-5-chloro-1-isopropyl-2-(4-methyl-1-piperazinyl)-benzimidazole

Guidance literature:: With hydrogenchloride; zinc; In ethanol; at 60 ℃; for 3h;
DOI:10.1248/cpb.41.1832

Reference yield:

: 148014-96-4
5-chloro-1-isopropyl-2-(4-methyl-1-piperazinyl)-6-nitrobenzimidazole

: 7440-66-6
zinc

: 148014-93-1
6-amino-5-chloro-1-isopropyl-2-(4-methyl-1-piperazinyl)-benzimidazole

Guidance literature:: In hydrogenchloride;

Reference yield:

: 109-01-3
1-methyl-piperazine

: 148014-93-1
6-amino-5-chloro-1-isopropyl-2-(4-methyl-1-piperazinyl)-benzimidazole

Guidance literature:: Multi-step reaction with 3 steps

1: xylene / 3 h / Heating

2: 58 percent / fum. HNO₃, acetic acid / 1 h / 50 °C

3: 73 percent / Zn (powder), conc. HCl / ethanol / 3 h / 60 °C

With hydrogenchloride; nitric acid; acetic acid; zinc; In ethanol; xylene;
DOI:10.1248/cpb.41.1832