Diethyl 2-(1-naphthyl)malonate

Base Information

Chemical Name:Diethyl 2-(1-naphthyl)malonate
CAS No.:6341-60-2
Molecular Formula:C₁₇H₁₈O₄
Molecular Weight:286.328
Hs Code.:2917399090
NSC Number:46725
DSSTox Substance ID:DTXSID70286637
Nikkaji Number:J1.702.936C
Wikidata:Q82022409
Mol file:6341-60-2.mol

Synonyms:6341-60-2;diethyl 2-(1-naphthyl)malonate;Diethyl 2-(naphthalen-1-yl)malonate;NSC 46725;NSC46725;EC-000.1829;SCHEMBL1433197;DTXSID70286637;NSC-46725;AKOS011682269;(1-Naphthyl)malonic acid diethyl ester;Diethyl 2-(naphthalen-1-yl)propanedioate;2-Naphthalen-1-yl-malonic acid diethyl ester;1,3-DIETHYL 2-(NAPHTHALEN-1-YL)PROPANEDIOATE

Suppliers and Price of Diethyl 2-(1-naphthyl)malonate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
DIETHYL-2-(1-NAPHTHYL)MALONATE 95.00%
5MG
$ 503.05

Total 5 raw suppliers

Chemical Property of Diethyl 2-(1-naphthyl)malonate

Chemical Property:

Vapor Pressure:2.03E-06mmHg at 25°C
Melting Point:61.3°C
Refractive Index:1.5450 (estimate)
Boiling Point:394.1°Cat760mmHg
Flash Point:193.4°C
PSA：52.60000
Density:1.161g/cm³
LogP:3.04960
XLogP3:3.8
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:7
Exact Mass:286.12050905
Heavy Atom Count:21
Complexity:348

Purity/Quality:: DIETHYL-2-(1-NAPHTHYL)MALONATE 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCOC(=O)C(C1=CC=CC2=CC=CC=C21)C(=O)OCC

Technology Process of Diethyl 2-(1-naphthyl)malonate

There total 13 articles about Diethyl 2-(1-naphthyl)malonate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

: 90-14-2
1-Iodonaphthalene

: 105-53-3
diethyl malonate

: 6341-60-2
diethyl 2-(1-naphthyl)malonate

Guidance literature:: With copper(l) iodide; caesium carbonate; 2-Phenylphenol; In tetrahydrofuran; at 70 ℃; for 30h;
DOI:10.1021/ol017038g

Reference yield: 84.0%

: 90-11-9
1-Bromonaphthalene

: 105-53-3
diethyl malonate

: 6341-60-2
diethyl 2-(1-naphthyl)malonate

Guidance literature:: With tri-tert-butyl phosphine; sodium hydride; bis(dibenzylideneacetone)-palladium⁽⁰⁾; In tetrahydrofuran; at 70 ℃; for 6h;
DOI:10.1021/jo016226h

Reference yield: 81.0%

: 2122-70-5
ethyl 2-(1-naphthyl)acetate

: 623-49-4
ethyl cyanoformate

: 6341-60-2
diethyl 2-(1-naphthyl)malonate

Guidance literature:: ethyl 2-(1-naphthyl)acetate; With lithium hexamethyldisilazane; In tetrahydrofuran; at -78 ℃; for 1h; Inert atmosphere;

ethyl cyanoformate; In tetrahydrofuran; at -78 - 20 ℃; Inert atmosphere;
DOI:10.1021/jo8025912