2H-1-Benzopyran-2-one, 3,4-dihydro-4-methyl-

Base Information

Chemical Name:2H-1-Benzopyran-2-one, 3,4-dihydro-4-methyl-
CAS No.:18435-75-1
Molecular Formula:C₁₀H₁₀O₂
Molecular Weight:162.188
Hs Code.:
NSC Number:19512
DSSTox Substance ID:DTXSID801268742
Nikkaji Number:J569.767K
Mol file:18435-75-1.mol

Synonyms:18435-75-1;2H-1-Benzopyran-2-one, 3,4-dihydro-4-methyl-;Hydrocoumarin, 4-methyl-;3,4-Dihydro-4-methylcoumarin;4-Methyl-1,2-benzodihydropyrone;NSC 19512;NSC19512;4-Methylchroman-2-one;4-methyl-chroman-2-one;3,4-Dihydro-4-methyl-2H-1-benzopyran-2-one;SCHEMBL8080906;3,4-di-hydro-4-methylcoumarin;DTXSID801268742;NSC-19512;LS-77233

Suppliers and Price of 2H-1-Benzopyran-2-one, 3,4-dihydro-4-methyl-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 5 raw suppliers

Chemical Property of 2H-1-Benzopyran-2-one, 3,4-dihydro-4-methyl-

Chemical Property:

Vapor Pressure:0.0634mmHg at 25°C
Boiling Point:231.1°Cat760mmHg
Flash Point:87.8°C
Density:1.127g/cm³
XLogP3:2
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:0
Exact Mass:162.068079557
Heavy Atom Count:12
Complexity:188

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1CC(=O)OC2=CC=CC=C12

Technology Process of 2H-1-Benzopyran-2-one, 3,4-dihydro-4-methyl-

There total 5 articles about 2H-1-Benzopyran-2-one, 3,4-dihydro-4-methyl- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 28.0%

: 1396690-36-0
2-(prop-1-en-2-yl)phenyl formate

: 13524-76-0
2,3-Dihydro-3,3-dimethylbenzofuran-2-one

: 18435-75-1,30825-54-8,30825-55-9
4-methyl-chroman-2-one

Guidance literature:: With dodecacarbonyl-triangulo-triruthenium; 2,4,5-trimethyl-1-phenyl-1H-imidazole; In 1,3,5-trimethyl-benzene; at 135 ℃; for 24h; Inert atmosphere;
DOI:10.1021/ol301850y

Reference yield:

: 294669-29-7
3-(2-hydroxyphenyl)cyclobutanone

: 607-71-6
4-methyl-2H-chromen-2-one

: 18435-75-1,30825-54-8,30825-55-9
4-methyl-chroman-2-one

Guidance literature:: bis(1,5-cyclooctadiene)rhodium(I) tetrafluoroborate; cyclohexyldiphenylphosphine; In m-xylene; at 140 ℃; for 3.5h;
DOI:10.1002/1521-3773(20000717)39:14<2484::AID-ANIE2484>3.0.CO;2-1

Reference yield:

: 118-93-4,104809-67-8
o-hydroxyacetophenone

: 13524-76-0
2,3-Dihydro-3,3-dimethylbenzofuran-2-one

: 18435-75-1,30825-54-8,30825-55-9
4-methyl-chroman-2-one

Guidance literature:: Multi-step reaction with 3 steps

1.1: potassium tert-butylate / tetrahydrofuran / 2 h / 20 °C

1.2: -78 - 30 °C

2.1: sodium hydrogencarbonate / neat (no solvent) / 20 °C

3.1: dodecacarbonyl-triangulo-triruthenium; 2,4,5-trimethyl-1-phenyl-1H-imidazole / 1,3,5-trimethyl-benzene / 24 h / 135 °C / Inert atmosphere

With dodecacarbonyl-triangulo-triruthenium; 2,4,5-trimethyl-1-phenyl-1H-imidazole; potassium tert-butylate; sodium hydrogencarbonate; In tetrahydrofuran; 1,3,5-trimethyl-benzene; 1.1: |Wittig Olefination / 1.2: |Wittig Olefination;
DOI:10.1021/ol301850y