4'',7-DIHYDROXY-5-METHOXY-8-PRENYLFLAVANONE

Base Information

• Chemical Name: 4'',7-DIHYDROXY-5-METHOXY-8-PRENYLFLAVANONE
• CAS No.: 72247-79-1
• Molecular Formula: C₂₁H₂₂O₄
• Molecular Weight: 338.403
• Mol file: 72247-79-1.mol

Synonyms:2-Propen-1-one,1-[2,6-dihydroxy-4-methoxy-3-(3-methyl-2-butenyl)phenyl]-3-phenyl-, (2E)-(9CI); 2-Propen-1-one,1-[2,6-dihydroxy-4-methoxy-3-(3-methyl-2-butenyl)phenyl]-3-phenyl-, (E)-;Isoxanthohumol; Isoxanthohumol (Helichrysum)

Chemical Property of 4'',7-DIHYDROXY-5-METHOXY-8-PRENYLFLAVANONE

Chemical Property:

• PSA: 66.76000
• LogP: 4.51120

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 4'',7-DIHYDROXY-5-METHOXY-8-PRENYLFLAVANONE

There total 7 articles about 4'',7-DIHYDROXY-5-METHOXY-8-PRENYLFLAVANONE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 71.0%

2',6'-di(methoxymethoxy)-4-methoxy-3-C-prenylchalcone → 2',6'-dihydroxy-4-methoxy-3-C-prenylchalcone (72247-79-1)

Guidance literature:

With hydrogenchloride; In methanol; for 0.25h; Heating;

Reference yield:

2,6-di(methoxymethoxy)-4-methoxyacetophenone (129750-75-0) → 2',6'-dihydroxy-4-methoxy-3-C-prenylchalcone (72247-79-1)

Guidance literature:

Multi-step reaction with 3 steps

1: 42.6 percent / KOH / methanol / 20 h / 20 °C

2: 69.87 percent / KOH / ethanol / 72 h / 20 °C

3: 71 percent / 3N HCl / methanol / 0.25 h / Heating

With hydrogenchloride; potassium hydroxide; In methanol; ethanol; 1: Alkylation / 2: Condensation / 3: demethoxymethylation;

Reference yield:

benzaldehyde (100-52-7) → 2',6'-dihydroxy-4-methoxy-3-C-prenylchalcone (72247-79-1)

Guidance literature:

Multi-step reaction with 2 steps

1: 69.87 percent / KOH / ethanol / 72 h / 20 °C

2: 71 percent / 3N HCl / methanol / 0.25 h / Heating

With hydrogenchloride; potassium hydroxide; In methanol; ethanol; 1: Condensation / 2: demethoxymethylation;

upstream raw materials:

1-(2,6-dihydroxy-4-methoxy-3-(3-methylbut-2-en-1-yl)phenyl)ethan-1-one

benzaldehyde

2,6-di(methoxymethoxy)-4-methoxyacetophenone

2,6-di(methoxymethoxy)-4-methoxy-3-C-prenylacetophenone

Downstream raw materials:

5-hydroxy-7-methoxy-3-C-prenylflavone