Ethyl 1-(4-fluorophenyl)sulfonylpiperidine-4-carboxylate

Base Information

Chemical Name:Ethyl 1-(4-fluorophenyl)sulfonylpiperidine-4-carboxylate
CAS No.:5352-24-9
Molecular Formula:C14H18FNO4S
Molecular Weight:315.3604
Hs Code.:2928000090
DSSTox Substance ID:DTXSID40351280
Wikidata:Q82127570
Mol file:5352-24-9.mol

Synonyms:ethyl 1-(4-fluorophenyl)sulfonylpiperidine-4-carboxylate;5352-24-9;ethyl 1-[(4-fluorophenyl)sulfonyl]-4-piperidinecarboxylate;ethyl 1-[(4-fluorophenyl)sulfonyl]piperidine-4-carboxylate;CBMicro_019123;Oprea1_311028;Oprea1_456492;SCHEMBL6237506;DTXSID40351280;ZTJRIPZDFXLFRK-UHFFFAOYSA-N;CCG-7066;STK068407;AKOS000665480;BIM-0018889.P001;AB00082333-01;AK-968/11164539;SR-01000521116;SR-01000521116-1;Z45525064;1-(4-Fluorophenylsulphonyl)-4-(ethoxycarbonyl)piperidine

Suppliers and Price of Ethyl 1-(4-fluorophenyl)sulfonylpiperidine-4-carboxylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Total 0 raw suppliers

Chemical Property of Ethyl 1-(4-fluorophenyl)sulfonylpiperidine-4-carboxylate

Chemical Property:

Vapor Pressure:3.16E-07mmHg at 25°C
Boiling Point:418.9°Cat760mmHg
Flash Point:207.1°C
PSA：72.06000
Density:1.297g/cm³
LogP:2.80820
XLogP3:1.9
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:5
Exact Mass:315.09405739
Heavy Atom Count:21
Complexity:446

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCOC(=O)C1CCN(CC1)S(=O)(=O)C2=CC=C(C=C2)F

Technology Process of Ethyl 1-(4-fluorophenyl)sulfonylpiperidine-4-carboxylate

There total 5 articles about Ethyl 1-(4-fluorophenyl)sulfonylpiperidine-4-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 69.0%

: 141-97-9
ethyl acetoacetate

: 121-88-0
5-Nitro-2-aminophenol

: 5352-24-9
1-ethoxy-2-(2-hydroxy-4-nitrophenylhydrazono)butane-1,3-dione

Guidance literature:: 5-Nitro-2-aminophenol; With hydrogenchloride; sodium hydroxide; sodium nitrite; In water; for 1h; Cooling with ice;

ethyl acetoacetate; With sodium acetate; In ethanol; water; at 0 ℃; pH=8 - 10;
DOI:10.1021/ic101516k

Reference yield:

: 141-97-9
ethyl acetoacetate

: 95-55-6
2-amino-phenol

: 5352-24-9
1-ethoxy-2-(2-hydroxy-4-nitrophenylhydrazono)butane-1,3-dione

Guidance literature:: 2-amino-phenol; With hydrogenchloride; sodium nitrite; In water; at 0 - 5 ℃;

ethyl acetoacetate; With sodium acetate; In ethanol;
DOI:10.1039/c5ra06658a