3-(2-Methylpiperidino)propyl=p-butoxybenzoate

Base Information

• Chemical Name: 3-(2-Methylpiperidino)propyl=p-butoxybenzoate
• CAS No.: 63916-68-7
• Molecular Formula: C₂₀H₃₁NO₃
• Molecular Weight: 333.471
• Hs Code.: 2933399090
• Mol file: 63916-68-7.mol

Synonyms:Benzoicacid, p-butoxy-, 3-(2-methylpiperidino)propyl ester (6CI,7CI)

Chemical Property of 3-(2-Methylpiperidino)propyl=p-butoxybenzoate

Chemical Property:

• Vapor Pressure: 2.92E-08mmHg at 25°C
• Boiling Point: 449.2°C at 760 mmHg
• Flash Point: 225.5°C
• PSA: 38.77000
• Density: 1.018g/cm³
• LogP: 4.22470

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 3-(2-Methylpiperidino)propyl=p-butoxybenzoate

There total 5 articles about 3-(2-Methylpiperidino)propyl=p-butoxybenzoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

4-butoxybenzoic acid (1498-96-0) → 4-butoxy-benzoic acid-[3-(2-methyl-piperidino)-propyl ester] (63916-68-7)

Guidance literature:

Multi-step reaction with 2 steps

1: thionyl chloride

2: ethanol

With thionyl chloride; ethanol;

DOI:10.1021/ja01216a051

Reference yield:

2-Methylpiperidin (109-05-7,3000-79-1) → 4-butoxy-benzoic acid-[3-(2-methyl-piperidino)-propyl ester] (63916-68-7)

Guidance literature:

Multi-step reaction with 2 steps

1: potassium carbonate / 160 °C

2: ethanol

With ethanol; potassium carbonate;

DOI:10.1021/ja01216a051

Reference yield:

4-hydroxy-benzoic acid (99-96-7) → 4-butoxy-benzoic acid-[3-(2-methyl-piperidino)-propyl ester] (63916-68-7)

Guidance literature:

Multi-step reaction with 3 steps

1: aqueous KOH-solution

2: thionyl chloride

3: ethanol

With potassium hydroxide; thionyl chloride; ethanol;

DOI:10.1021/ja01216a051

upstream raw materials:

2-methylpiperidine-1-propanol

4-(n-butyloxy)benzoyl chloride

1-(3-chloro-propyl)-2-methyl-piperidine

4-butoxybenzoic acid