N,2,2-Triphenylacetamide

Base Information

• Chemical Name: N,2,2-Triphenylacetamide
• CAS No.: 4695-14-1
• Molecular Formula: C20H17NO
• Molecular Weight: 287.361
• Hs Code.: 2924299090
• European Community (EC) Number: 652-120-3
• NSC Number: 74688
• DSSTox Substance ID: DTXSID50291289
• Nikkaji Number: J122.213I
• Wikidata: Q82029201
• ChEMBL ID: CHEMBL1467571
• Mol file: 4695-14-1.mol

Synonyms:N,2,2-Triphenylacetamide;4695-14-1;Acetanilide, 2,2-diphenyl-;2,2-Diphenylacetanilide;Benzeneacetamide, N,.alpha.-diphenyl-;ACETANILIDE,2,2-DIPHENYL-;NSC74688;Acetanilide,2-diphenyl-;Cambridge id 5245955;N,2,2-triphenyl-acetamide;TimTec1_000842;NCIOpen2_004134;Oprea1_697654;MLS001164702;N,2,2-Triphenylacetamide #;SCHEMBL1383257;CHEMBL1467571;DTXSID50291289;Benzeneacetamide,.alpha.-diphenyl-;HMS1536G06;HMS2863F05;NSC 74688;NSC-74688;STK294371;AKOS001076073;AS-0459;NCGC00175065-01;NCGC00175065-02;SMR000539817;CS-0239709;EN300-218050;AB00833251-07;BRD-K89195027-001-01-4;Z27782755

Chemical Property of N,2,2-Triphenylacetamide

Chemical Property:

• Vapor Pressure: 2.51E-10mmHg at 25°C
• Boiling Point: 505.1°Cat760mmHg
• Flash Point: 306.1°C
• PSA: 29.10000
• Density: 1.163g/cm³
• LogP: 4.53020
• XLogP3: 4.4
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 4
• Exact Mass: 287.131014166
• Heavy Atom Count: 22
• Complexity: 318

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC=C(C=C1)C(C2=CC=CC=C2)C(=O)NC3=CC=CC=C3

Technology Process of N,2,2-Triphenylacetamide

There total 50 articles about N,2,2-Triphenylacetamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

2,2,N-triphenyl-acetamide oxime (81838-77-9) → 2,2-diphenylacetanilide (4695-14-1)

Guidance literature:

With sulfuric acid; sodium dodecyl sulfate; sodium nitrite;

Reference yield: 92.0%

2,2-diphenylacetic acid (117-34-0) + N-tert-butyl-N'-phenyl-S-phenylisothiourea → 2,2-diphenylacetanilide (4695-14-1)

Guidance literature:

With iron(III)-acetylacetonate; In iso-butanol; at 98 ℃; for 24h; Microwave irradiation;

DOI:10.1021/acs.orglett.6b02247

Reference yield: 91.0%

4-chlorophenyldiphenylacetamide (24765-98-8) → 2,2-diphenylacetanilide (4695-14-1)

Guidance literature:

With dimethylamine borane; potassium carbonate; triphenylphosphine; bis(triphenylphosphine)nickel(II) chloride; In acetonitrile; at 40 ℃; for 12h;

DOI:10.1016/S0040-4039(01)01522-2

upstream raw materials:

triphenylketeneimine

diphenyl-acetic acid-(N-phenyl-hydrazide)

3,3,6,6-tetraphenyl-2,5-p-dioxanedione

aniline

Downstream raw materials:

N,2,2-triphenyl-2-chloroacetimidoyl chloride

Diphenylacetyl-phenyl-carbamic acid isopropyl ester

3,3-diphenyl-1,3-dihydro-indol-2-one

benzilanilide