Quinoxaline-2,3-dimethanol, 6-fluoro-, 1,4-dioxide

Base Information

Chemical Name:Quinoxaline-2,3-dimethanol, 6-fluoro-, 1,4-dioxide
CAS No.:84044-38-2
Molecular Formula:C₁₀H₉FN₂O₄
Molecular Weight:240.191
Hs Code.:2933990090
DSSTox Substance ID:DTXSID80232943
Nikkaji Number:J59.558F
Wikidata:Q83114177
Mol file:84044-38-2.mol

Synonyms:84044-38-2;BRN 5055778;Quinoxaline-2,3-dimethanol, 6-fluoro-, 1,4-dioxide;6-Fluoro-quinoxaline-2,3-dimethanol 1,4-dioxide;6-Fluoro-2,3-bis(hydroxymethyl)quinoxaline 1,4-di-N-oxide;C10H9FN2O4;DTXSID80232943;C10-H9-F-N2-O4;LS-143021;6-Fluoroquinoxaline-2,3-dimethanol 1,4-dioxide

Suppliers and Price of Quinoxaline-2,3-dimethanol, 6-fluoro-, 1,4-dioxide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
6-FLUORO-2,3-BIS(HYDROXYMETHYL)QUINOXALINE 1,4-DI-N-OXIDE 95.00%
5MG
$ 497.75

Total 3 raw suppliers

Chemical Property of Quinoxaline-2,3-dimethanol, 6-fluoro-, 1,4-dioxide

Chemical Property:

Boiling Point:°Cat760mmHg
Flash Point:°C
PSA：91.38000
Density:g/cm³
LogP:0.82050
XLogP3:-0.6
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:2
Exact Mass:240.05463493
Heavy Atom Count:17
Complexity:360

Purity/Quality:: 6-FLUORO-2,3-BIS(HYDROXYMETHYL)QUINOXALINE 1,4-DI-N-OXIDE 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC2=C(C=C1F)N(C(=C([N+]2=O)CO)CO)[O-]

Technology Process of Quinoxaline-2,3-dimethanol, 6-fluoro-, 1,4-dioxide

There total 4 articles about Quinoxaline-2,3-dimethanol, 6-fluoro-, 1,4-dioxide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 63.0%

: 84044-37-1
6-Fluoro-2,3-bis(acetoxymethyl)quinoxaline 1,4-di-N-oxide

: 84044-38-2
6-Fluoro-2,3-bis(hydroxymethyl)quinoxaline 1,4-di-N-oxide

Guidance literature:: With sodium hydroxide; In methanol; at 20 - 22 ℃; for 0.75h;
DOI:10.1007/BF00773092

Reference yield:

: 84044-35-9
6-Fluoro-2,3-dimethylquinoxaline 1,4-di-N-oxide

: 84044-38-2
6-Fluoro-2,3-bis(hydroxymethyl)quinoxaline 1,4-di-N-oxide

Guidance literature:: Multi-step reaction with 3 steps

1: 99 percent / Br₂ / CH₂Cl₂; dimethylformamide / 3 h / 58 °C

2: 54.7 percent / Et₃N / acetone / 0.5 h / Heating

3: 63 percent / NaOH / methanol / 0.75 h / 20 - 22 °C

With sodium hydroxide; bromine; triethylamine; In methanol; dichloromethane; N,N-dimethyl-formamide; acetone;
DOI:10.1007/BF00773092

Reference yield:

: 84044-36-0
6-Fluoro-2,3-bis(bromomethyl)quinoxaline 1,4-di-N-oxide

: 84044-38-2
6-Fluoro-2,3-bis(hydroxymethyl)quinoxaline 1,4-di-N-oxide

Guidance literature:: Multi-step reaction with 2 steps

1: 54.7 percent / Et₃N / acetone / 0.5 h / Heating

2: 63 percent / NaOH / methanol / 0.75 h / 20 - 22 °C

With sodium hydroxide; triethylamine; In methanol; acetone;
DOI:10.1007/BF00773092