samanine

Base Information

Chemical Name:samanine
CAS No.:22614-24-0
Molecular Formula:C₁₉H₃₃NO
Molecular Weight:291.477
Hs Code.:
Mol file:22614-24-0.mol

Synonyms:3-Aza-A-homoandrostan-16-ol,(5b,16b)-; Samandarine, 1,4-deoxy- (8CI); 3-Aza-A-homo-5b-androstan-16b-ol (8CI);Cyclopenta[5,6]naphth[1,2-d]azepin-9-ol, octadecahydro-5a,7a-dimethyl-,[5aS-(5aa,5bb,7aa,9a,10ab,10ba,12aa)]-; Samanin; Samanine

Suppliers and Price of samanine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Total 0 raw suppliers

Chemical Property of samanine

Chemical Property:

Vapor Pressure:3.5E-08mmHg at 25°C
Boiling Point:403.3°Cat760mmHg
Flash Point:72.9°C
PSA：32.26000
Density:1.023g/cm³
LogP:3.91830

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Description This novel alkaloid has been obtained from the toxic secretion of Salamandra maculosa taeniata. The structure given has been elucidated from chemical transformations and spectroscopic analysis and confirmed by synthesis.

Technology Process of samanine

There total 11 articles about samanine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1045-69-8
testosterone acetate

: 22614-24-0
samanine

Guidance literature:: Multi-step reaction with 9 steps

1: 97 percent / H₂ / Pd-black / pyridine / 16 h

2: 99 percent / toluene-p-sulphonic acid / benzene / 56 h / Heating

3: 94 percent / Na / methanol / 12 h / Ambient temperature

4: 78 percent / tetrahydrofuran / 16 h / Heating

5: 91 percent / 2 h / 15 Torr / pyrolysis: 210 deg C bath temp.

6: 1.) 9-BBN; 2.) aq. NaOH, 30percent H₂O₂, K₂CO₃ / 1.) THF, 60 deg C, 16 h; 2.) ice-water-bath, 1 h

7: 97 percent / aq. HCl / tetrahydrofuran / 18 h / Ambient temperature

8: 87 percent / PPh₃, diethyl azodicarboxylate (DEAD) / benzene / 24 h / Heating

9: 1.) HN₃, conc. H₂SO₄; 2.) LiAlH₄ / 1.) CHCl₃, 0 deg C, 20 min; 2.) THF, reflux, 20 h

With hydrogenchloride; sodium hydroxide; lithium aluminium tetrahydride; 9-borabicyclo[3.3.1]nonane dimer; tris-(2-chloro-ethyl)-amine; sulfuric acid; hydrogen; dihydrogen peroxide; sodium; potassium carbonate; toluene-4-sulfonic acid; triphenylphosphine; diethylazodicarboxylate; palladium; In tetrahydrofuran; pyridine; methanol; benzene;

Reference yield:

: 1164-92-7
17β-acetoxy-5β-androstan-3-one

: 22614-24-0
samanine

Guidance literature:: Multi-step reaction with 8 steps

1: 99 percent / toluene-p-sulphonic acid / benzene / 56 h / Heating

2: 94 percent / Na / methanol / 12 h / Ambient temperature

3: 78 percent / tetrahydrofuran / 16 h / Heating

4: 91 percent / 2 h / 15 Torr / pyrolysis: 210 deg C bath temp.

5: 1.) 9-BBN; 2.) aq. NaOH, 30percent H₂O₂, K₂CO₃ / 1.) THF, 60 deg C, 16 h; 2.) ice-water-bath, 1 h

6: 97 percent / aq. HCl / tetrahydrofuran / 18 h / Ambient temperature

7: 87 percent / PPh₃, diethyl azodicarboxylate (DEAD) / benzene / 24 h / Heating

8: 1.) HN₃, conc. H₂SO₄; 2.) LiAlH₄ / 1.) CHCl₃, 0 deg C, 20 min; 2.) THF, reflux, 20 h

With hydrogenchloride; sodium hydroxide; lithium aluminium tetrahydride; 9-borabicyclo[3.3.1]nonane dimer; tris-(2-chloro-ethyl)-amine; sulfuric acid; dihydrogen peroxide; sodium; potassium carbonate; toluene-4-sulfonic acid; triphenylphosphine; diethylazodicarboxylate; In tetrahydrofuran; methanol; benzene;

Reference yield:

: 16375-21-6
3,3-Ethylenedioxy-5β-androstan-17β-yl Acetate

: 22614-24-0
samanine

Guidance literature:: Multi-step reaction with 7 steps

1: 94 percent / Na / methanol / 12 h / Ambient temperature

2: 78 percent / tetrahydrofuran / 16 h / Heating

3: 91 percent / 2 h / 15 Torr / pyrolysis: 210 deg C bath temp.

4: 1.) 9-BBN; 2.) aq. NaOH, 30percent H₂O₂, K₂CO₃ / 1.) THF, 60 deg C, 16 h; 2.) ice-water-bath, 1 h

5: 97 percent / aq. HCl / tetrahydrofuran / 18 h / Ambient temperature

6: 87 percent / PPh₃, diethyl azodicarboxylate (DEAD) / benzene / 24 h / Heating

7: 1.) HN₃, conc. H₂SO₄; 2.) LiAlH₄ / 1.) CHCl₃, 0 deg C, 20 min; 2.) THF, reflux, 20 h

With hydrogenchloride; sodium hydroxide; lithium aluminium tetrahydride; 9-borabicyclo[3.3.1]nonane dimer; tris-(2-chloro-ethyl)-amine; sulfuric acid; dihydrogen peroxide; sodium; potassium carbonate; triphenylphosphine; diethylazodicarboxylate; In tetrahydrofuran; methanol; benzene;