6-Methylindan-5-ol

Base Information

• Chemical Name: 6-Methylindan-5-ol
• CAS No.: 20294-39-7
• Molecular Formula: C10H12O
• Molecular Weight: 148.205
• Hs Code.: 2906299090
• European Community (EC) Number: 243-709-2
• DSSTox Substance ID: DTXSID80174177
• Nikkaji Number: J280.559F
• Wikidata: Q83044236
• Mol file: 20294-39-7.mol

Synonyms:6-Methylindan-5-ol;20294-39-7;6-methyl-2,3-dihydro-1H-inden-5-ol;EINECS 243-709-2;1H-Inden-5-ol, 2,3-dihydro-6-methyl-;6-Methyl-5-hydroxy-indan;SCHEMBL19931597;DTXSID80174177

Chemical Property of 6-Methylindan-5-ol

Chemical Property:

• Vapor Pressure: 0.00415mmHg at 25°C
• Boiling Point: 270.3°Cat760mmHg
• Flash Point: 121.5°C
• PSA: 20.23000
• Density: 1.112g/cm³
• LogP: 2.18930
• XLogP3: 2.8
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 0
• Exact Mass: 148.088815002
• Heavy Atom Count: 11
• Complexity: 144

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC1=CC2=C(CCC2)C=C1O

Technology Process of 6-Methylindan-5-ol

There total 17 articles about 6-Methylindan-5-ol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

6-Hydroxymethyl-5-indanol (82472-15-9) → 6-methyl-2,3-dihydro-1H-inden-5-ol (20294-39-7)

Guidance literature:

With potassium hydroxide; hydrogen; nickel; In methanol; for 14h; under 760.051 Torr;

DOI:10.1021/jo702168s

Reference yield: 71.0%

hepta-1,6-diyne (2396-63-6) → 6-methyl-2,3-dihydro-1H-inden-5-ol (20294-39-7)

Guidance literature:

In acetonitrile; at 70 ℃; for 133h;

DOI:10.1021/ja00290a053

Reference yield: 61.0%

hepta-1,6-diyne (2396-63-6) → 6-methyl-2,3-dihydro-1H-inden-5-ol (20294-39-7)

Guidance literature:

In tetrahydrofuran; at 21 ℃; for 5h;

DOI:10.1021/jo00391a016

upstream raw materials:

5-Methoxy-6-methyl-indan

6-Methoxy-6-methyl-1,2,3,6-tetrahydro-inden-5-one

hydrogenchloride

5-methoxy-6-methyl-1-indanone

Downstream raw materials:

6-methyl-2,3-dihydro-1H-inden-5-yl-3,5-dinitrobenzoate

Refernces

• 1、 Hashmi, A. Stephen K.,Haeffner, Tobias,Rudolph, Matthias,Rominger, Frank. "Gold catalysis: Domino reaction of En-diynes to highly substituted phenols". supporting information; experimental part. p. 8195 - 8201. Retrieved 2011/09/12.
• 2、 Xu, Yao-Chang,Wulff, William D.. "Alkylations of Tetracarbonyl(phosphine)chromium and Pentacarbonylchromium Carbene Complexes and Their Reactions with Selected Acetylenes". . p. 3263 - 3275. Retrieved 2007/10/02.