tert-Butyloxycarbonyl-phenylalanyl-phenylalanyl-glycine hydroxylamine

Base Information

Chemical Name:tert-Butyloxycarbonyl-phenylalanyl-phenylalanyl-glycine hydroxylamine
CAS No.:97207-35-7
Molecular Formula:C25H32 N4 O6
Molecular Weight:0
Hs Code.:
DSSTox Substance ID:DTXSID60914058
Nikkaji Number:J490.756F
Wikidata:Q82884795
Mol file:97207-35-7.mol

Synonyms:Boc-Phe-Phe-Gly-NHOH;tert-butyloxycarbonyl-phenylalanyl-phenylalanyl-glycine hydroxylamine

Suppliers and Price of tert-Butyloxycarbonyl-phenylalanyl-phenylalanyl-glycine hydroxylamine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 2 raw suppliers

Chemical Property of tert-Butyloxycarbonyl-phenylalanyl-phenylalanyl-glycine hydroxylamine

Chemical Property:

Melting Point:92 - 97 °C
PSA：145.86000
Density:1.233g/cm³
LogP:3.03510
XLogP3:1.8
Hydrogen Bond Donor Count:5
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:12
Exact Mass:484.23218475
Heavy Atom Count:35
Complexity:711

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC(C)(C)OC(=O)NC(CC1=CC=CC=C1)C(=O)NC(CC2=CC=CC=C2)C(=O)NCC(=O)NO
Isomeric SMILES:CC(C)(C)OC(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N[C@@H](CC2=CC=CC=C2)C(=O)NCC(=O)NO

Technology Process of tert-Butyloxycarbonyl-phenylalanyl-phenylalanyl-glycine hydroxylamine

There total 5 articles about tert-Butyloxycarbonyl-phenylalanyl-phenylalanyl-glycine hydroxylamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 51.6%

: 62307-54-4
Boc-Phe-Phe-Gly-OEt

: 97207-35-7
Boc-Phe-Phe-Gly-NHOH

Guidance literature:: With sodium hydroxide; hydroxylamine; In ethanol; for 48h;
DOI:10.1016/0223-5234(92)90001-H

Reference yield:

: 13734-34-4
N-tert-butoxycarbonyl-L-phenylalanine

: 97207-35-7
Boc-Phe-Phe-Gly-NHOH

Guidance literature:: Multi-step reaction with 4 steps

1: 59.6 percent / IBCF, NMM

2: 93 percent / 1 N NaOH / H₂O; dioxane / 2 h / Ambient temperature

3: DCC, HOBt, NMM

4: 51.6 percent / 1 M NH₂OH, NaOH / ethanol / 48 h

With 4-methyl-morpholine; sodium hydroxide; hydroxylamine; benzotriazol-1-ol; dicyclohexyl-carbodiimide; isobutyl chloroformate; In 1,4-dioxane; ethanol; water;
DOI:10.1016/0223-5234(92)90001-H

Reference yield:

: 13122-90-2
Boc-Phe-Phe-OH

: 97207-35-7
Boc-Phe-Phe-Gly-NHOH

Guidance literature:: Multi-step reaction with 2 steps

1: DCC, HOBt, NMM

2: 51.6 percent / 1 M NH₂OH, NaOH / ethanol / 48 h

With 4-methyl-morpholine; sodium hydroxide; hydroxylamine; benzotriazol-1-ol; dicyclohexyl-carbodiimide; In ethanol;
DOI:10.1016/0223-5234(92)90001-H