3-HYDROXYBUTANOHYDRAZIDE

Base Information

• Chemical Name: 3-HYDROXYBUTANOHYDRAZIDE
• CAS No.: 24534-93-8
• Molecular Formula: C₄H₁₀N₂O₂
• Molecular Weight: 118.136
• Hs Code.: 2928000090
• Mol file: 24534-93-8.mol

Synonyms:Butyricacid, 3-hydroxy-, hydrazide (6CI,7CI,8CI); 3-Hydroxybutanoic acid hydrazide;3-Hydroxybutyric acid hydrazide; NSC 523822

Chemical Property of 3-HYDROXYBUTANOHYDRAZIDE

Chemical Property:

• Vapor Pressure: 3.85E-06mmHg at 25°C
• Melting Point: 126-128 °C
• Boiling Point: 345.5°Cat760mmHg
• PKA: 13.16±0.18(Predicted)
• Flash Point: 162.8°C
• PSA: 75.35000
• Density: 1.157g/cm³
• LogP: -0.16160

Purity/Quality:

98%min ^*data from raw suppliers

3-Hydroxybutanohydrazide ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 3-HYDROXYBUTANOHYDRAZIDE

There total 5 articles about 3-HYDROXYBUTANOHYDRAZIDE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 83.0%

ethyl 3-hydroxybutyrate (5405-41-4) → (±)-3-hydroxybutanehydrazide (24534-93-8)

Guidance literature:

With hydrazine hydrate; In methanol; water; at 20 ℃; for 5h; Cooling with ice;

DOI:10.3390/molecules21111543

Reference yield:

3-hydroxybutyric acid methyl ester (1487-49-6) → (±)-3-hydroxybutanehydrazide (24534-93-8)

Guidance literature:

With methanol; hydrazine hydrate;

DOI:10.1002/hlca.19570400533

Reference yield:

4-methyloxetan-2-one (3068-88-0,32082-74-9,36536-46-6,65058-82-4) → (±)-3-hydroxybutanehydrazide (24534-93-8)

Guidance literature:

With hydrazine hydrate;

upstream raw materials:

4-methyloxetan-2-one

ethyl 3-hydroxybutyrate

3-hydroxybutyric acid methyl ester

Downstream raw materials:

3-Hydroxy-butyric acid [1-(2-chloro-phenyl)-eth-(E)-ylidene]-hydrazide

3-Hydroxy-butyric acid [1-(2-chloro-phenyl)-meth-(E)-ylidene]-hydrazide