(E)-3-Hydroxybutanoic acid (1-(2-chlorophenyl)ethylidene)hydrazide

Base Information

• Chemical Name: (E)-3-Hydroxybutanoic acid (1-(2-chlorophenyl)ethylidene)hydrazide
• CAS No.: 133661-87-7
• Molecular Formula: C₁₂H₁₅ClN₂O₂
• Molecular Weight: 254.716
• Nikkaji Number: J363.840E
• Mol file: 133661-87-7.mol

Synonyms:BRN 4256334;(E)-3-Hydroxybutanoic acid (1-(2-chlorophenyl)ethylidene)hydrazide;Butanoic acid, 3-hydroxy-, (1-(2-chlorophenyl)ethylidene)hydrazide, (E)-;133661-87-7;LS-46314;N'-(2-Chloro-alpha-methylbenzylidene)-3-hydroxybutanoic acid hydrazide

Chemical Property of (E)-3-Hydroxybutanoic acid (1-(2-chlorophenyl)ethylidene)hydrazide

Chemical Property:

• Boiling Point: °Cat760mmHg
• Flash Point: °C
• Density: 1.21g/cm³
• XLogP3: 1.7
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 4
• Exact Mass: 254.0822054
• Heavy Atom Count: 17
• Complexity: 294

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC(CC(=O)NN=C(C)C1=CC=CC=C1Cl)O
• Isomeric SMILES: CC(CC(=O)N/N=C(\C)/C1=CC=CC=C1Cl)O

Technology Process of (E)-3-Hydroxybutanoic acid (1-(2-chlorophenyl)ethylidene)hydrazide

There total 1 articles about (E)-3-Hydroxybutanoic acid (1-(2-chlorophenyl)ethylidene)hydrazide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 71.0%

(±)-3-hydroxybutanehydrazide (24534-93-8) + 1-(2-chlorophenyl)ethanone (2142-68-9) → 3-Hydroxy-butyric acid [1-(2-chloro-phenyl)-eth-(E)-ylidene]-hydrazide (133661-87-7,133662-61-0)

Guidance literature:

In ethanol; water; for 4h; Heating;

DOI:10.1016/0223-5234(90)90198-C

upstream raw materials:

(±)-3-hydroxybutanehydrazide

1-(2-chlorophenyl)ethanone