(E)-7-Methyl-1,3-dipropyl-8-(2,3,4-trimethoxystyryl)xanthine

Base Information

Chemical Name:(E)-7-Methyl-1,3-dipropyl-8-(2,3,4-trimethoxystyryl)xanthine
CAS No.:147700-52-5
Molecular Formula:C₂₃H₃₀N₄O₅
Molecular Weight:442.515
Hs Code.:
Nikkaji Number:J551.333B
Wikidata:Q76389259
ChEMBL ID:CHEMBL283937

Synonyms:(E)-7-Methyl-1,3-dipropyl-8-(2,3,4-trimethoxystyryl)xanthine;CHEMBL283937;1H-Purine-2,6-dione, 3,7-dihydro-1,3-dipropyl-7-methyl-8-(2-(2,3,4-trimethoxyphenyl)ethenyl)-,(E)-;147700-52-5;SCHEMBL7729947;SCHEMBL7729954;BDBM50047171;LS-126992;1,3-Dipropyl-7-methyl-8-(2,3,4-trimethoxystyryl)xanthine;7-Methyl-1,3-dipropyl-8-[(E)-2-(2,3,4-trimethoxy-phenyl)-vinyl]-3,7-dihydro-purine-2,6-dione;7-Methyl-1,3-dipropyl-8-[2-(2,3,4-trimethoxy-phenyl)-vinyl]-3,7-dihydro-purine-2,6-dione

Suppliers and Price of (E)-7-Methyl-1,3-dipropyl-8-(2,3,4-trimethoxystyryl)xanthine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (E)-7-Methyl-1,3-dipropyl-8-(2,3,4-trimethoxystyryl)xanthine

Chemical Property:

Vapor Pressure:5.83E-16mmHg at 25°C
Boiling Point:633.6°Cat760mmHg
Flash Point:337°C
Density:1.21g/cm³
XLogP3:3.6
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:9
Exact Mass:442.22162007
Heavy Atom Count:32
Complexity:689

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCCN1C2=C(C(=O)N(C1=O)CCC)N(C(=N2)C=CC3=C(C(=C(C=C3)OC)OC)OC)C
Isomeric SMILES:CCCN1C2=C(C(=O)N(C1=O)CCC)N(C(=N2)/C=C/C3=C(C(=C(C=C3)OC)OC)OC)C

Technology Process of (E)-7-Methyl-1,3-dipropyl-8-(2,3,4-trimethoxystyryl)xanthine

There total 6 articles about (E)-7-Methyl-1,3-dipropyl-8-(2,3,4-trimethoxystyryl)xanthine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

: 147700-51-4
(E)-1,3-Dipropyl-8-(2,3,4-trimethoxystyryl)xanthine

: 74-88-4
methyl iodide

: 147700-52-5
(E)-7-Methyl-1,3-dipropyl-8-(2,3,4-trimethoxystyryl)xanthine

Guidance literature:: With potassium carbonate; In N,N-dimethyl-formamide; at 60 ℃; for 0.5h;
DOI:10.1021/jm00062a005

Reference yield: 66.0%

: 147700-52-5
(E)-7-Methyl-1,3-dipropyl-8-(2,3,4-trimethoxystyryl)xanthine

Guidance literature:

Reference yield:

: 5-amino-6-nitroso-1,3-dipropyluracil

: 147700-52-5
(E)-7-Methyl-1,3-dipropyl-8-(2,3,4-trimethoxystyryl)xanthine

Guidance literature:: Multi-step reaction with 4 steps

1: H₂ / 5percent Pd/C / dimethylformamide / 2068.6 Torr

2: 1-<3-(dimethylamino)propyl>-3-ethylcarbodiimide hydrochloride, 4-(N,N-dimethylamino)pyridine, imidazole / dimethylformamide / 3 h / Ambient temperature

3: 4 N aq. NaOH / methanol / 2 h / 60 °C

4: 88 percent / K₂CO₃ / dimethylformamide / 0.5 h / 60 °C

With 1H-imidazole; dmap; sodium hydroxide; hydrogen; potassium carbonate; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; palladium on activated charcoal; In methanol; N,N-dimethyl-formamide;
DOI:10.1021/jm00062a005