Spiro(benzo(b)cyclopenta(e)(1,4)diazepine-10(9H),1'-cyclopentane)-9-ethanamine, 1,2,3,10a-tetrahydro-N-(4-methoxyphenyl)-

Base Information

• Chemical Name: Spiro(benzo(b)cyclopenta(e)(1,4)diazepine-10(9H),1'-cyclopentane)-9-ethanamine, 1,2,3,10a-tetrahydro-N-(4-methoxyphenyl)-
• CAS No.: 133307-93-4
• Molecular Formula: C₂₅H₃₁N₃O
• Molecular Weight: 389.541
• DSSTox Substance ID: DTXSID70928060
• Nikkaji Number: J362.644J

Synonyms:BRN 4335453;133307-93-4;Spiro(benzo(b)cyclopenta(e)(1,4)diazepine-10(9H),1'-cyclopentane)-9-ethanamine, 1,2,3,10a-tetrahydro-N-(4-methoxyphenyl)-;DTXSID70928060;LS-145803;4-Methoxy-N-[2-(1,2,3,10a-tetrahydro-9H-spiro[benzo[b]cyclopenta[e][1,4]diazepine-10,1'-cyclopentan]-9-yl)ethyl]aniline;9-[2-(4-Methoxyanilino)ethyl]-1,2,3,9,10,10a-hexahydrospiro[benzo[b]cyclopenta[e][1,4]diazepine-10,1'-cyclopentane]

Chemical Property of Spiro(benzo(b)cyclopenta(e)(1,4)diazepine-10(9H),1'-cyclopentane)-9-ethanamine, 1,2,3,10a-tetrahydro-N-(4-methoxyphenyl)-

Chemical Property:

• Boiling Point: 584.7°Cat760mmHg
• Flash Point: 307.4°C
• Density: 1.2g/cm³
• XLogP3: 4.7
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 5
• Exact Mass: 389.246712621
• Heavy Atom Count: 29
• Complexity: 577

Purity/Quality:

85.0-99.8% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: COC1=CC=C(C=C1)NCCN2C3=CC=CC=C3N=C4CCCC4C25CCCC5

Technology Process of Spiro(benzo(b)cyclopenta(e)(1,4)diazepine-10(9H),1'-cyclopentane)-9-ethanamine, 1,2,3,10a-tetrahydro-N-(4-methoxyphenyl)-

There total 2 articles about Spiro(benzo(b)cyclopenta(e)(1,4)diazepine-10(9H),1'-cyclopentane)-9-ethanamine, 1,2,3,10a-tetrahydro-N-(4-methoxyphenyl)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 50.0%

9-(2-bromoethyl)-2,3,9,10a-tetrahydrospiro(benzocyclopenta<1.4>diazepine-10(1H),1'-cyclopentane) (93464-37-0) + 4-methoxy-aniline (104-94-9) → C25H31N3O (133307-93-4)

Guidance literature:

With triethylamine; In ethanol; for 3h; Heating;

Reference yield:

2,3-cyclopentano-3,4-dihydro-5H-4-spirocyclopentano-1,5-benzodiazepine (41526-78-7) → C25H31N3O (133307-93-4)

Guidance literature:

Multi-step reaction with 2 steps

1: 1) NaOEt / 1) EtOH, RT, 30 min, 2) 80 deg C, 2h

2: 50 percent / NEt₃ / ethanol / 3 h / Heating

With sodium ethanolate; triethylamine; In ethanol;

upstream raw materials:

9-(2-bromoethyl)-2,3,9,10a-tetrahydrospiro(benzocyclopenta<1.4>diazepine-10(1H),1'-cyclopentane)

4-methoxy-aniline

2,3-cyclopentano-3,4-dihydro-5H-4-spirocyclopentano-1,5-benzodiazepine

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 133307-93-4 Spiro(benzo(b)cyclopenta(e)(1,4)diazepine-10(9H),1-cyclopentane)-9-ethanamine, 1,2,3,10a-tetrahydro-N-(4-methoxyphenyl)-

Send

Send

Metric Ton KG G Pound L ML

Send

Send