(R,S)-3,3'-(1,2-Ethanediyl)bis(2-(3-pyridinyl)-4-thiazolidinone)

Base Information

Chemical Name:(R*,S*)-3,3'-(1,2-Ethanediyl)bis(2-(3-pyridinyl)-4-thiazolidinone)
CAS No.:131420-44-5
Molecular Formula:C₁₈H₁₈N₄O₂S₂
Molecular Weight:386.499
Hs Code.:
DSSTox Substance ID:DTXSID90927191
Wikidata:Q76279285
Mol file:131420-44-5.mol

Synonyms:BRN 4239698;(R*,S*)-3,3'-(1,2-Ethanediyl)bis(2-(3-pyridinyl)-4-thiazolidinone);(R*,R*)-(+-)-3,3'-(1,2-Ethanediyl)bis(2-(2-pyridinyl)-4-thiazolidinone);4-Thiazolidinone, 3,3'-(1,2-ethanediyl)bis(2-(2-pyridinyl)-, (R*,R*)-(+-)-;4-Thiazolidinone, 3,3'-(1,2-ethanediyl)bis(2-(3-pyridinyl)-, (R*,S*)-;131420-43-4;131420-44-5;DTXSID90927191;LS-151733;LS-151736;3,3'-(Ethane-1,2-diyl)bis[2-(pyridin-3-yl)-1,3-thiazolidin-4-one]

Suppliers and Price of (R*,S*)-3,3'-(1,2-Ethanediyl)bis(2-(3-pyridinyl)-4-thiazolidinone)

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of (R*,S*)-3,3'-(1,2-Ethanediyl)bis(2-(3-pyridinyl)-4-thiazolidinone)

Chemical Property:

Boiling Point:719.4°Cat760mmHg
Flash Point:388.9°C
PSA：117.00000
Density:1.38g/cm³
LogP:2.20060
XLogP3:1.2
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:5
Exact Mass:386.08711818
Heavy Atom Count:26
Complexity:489

Purity/Quality:: 85.0-99.8% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1C(=O)N(C(S1)C2=CN=CC=C2)CCN3C(SCC3=O)C4=CN=CC=C4
Isomeric SMILES:C1C(=O)N([C@H](S1)C2=CN=CC=C2)CCN3[C@H](SCC3=O)C4=CN=CC=C4

Technology Process of (R*,S*)-3,3'-(1,2-Ethanediyl)bis(2-(3-pyridinyl)-4-thiazolidinone)

There total 3 articles about (R*,S*)-3,3'-(1,2-Ethanediyl)bis(2-(3-pyridinyl)-4-thiazolidinone) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 86.0%

: 500-22-1
3-pyridinecarboxaldehyde

: 68-11-1
mercaptoacetic acid

: 107-15-3,85404-18-8
ethylenediamine

: 205688-81-9,131420-44-5
3,3'-(ethane-1,2-diyl)bis(2-(pyridin-3-yl)thiazolidin-4-one)

Guidance literature:: With nano-colloidal silica-tethered polyhedral oligomeric silsesquioxanes with eight branches of 3-aminopropyltriethoxysilane; In toluene; for 0.333333h; Sonication;
DOI:10.1515/znb-2017-0091

Reference yield: 40.0%

: 68-11-1
mercaptoacetic acid

: N,N’-bis[1-pyridin-3-ylmeth-(E)-ylidene]ethane-1,2-diamine

: 205688-81-9,131420-44-5
3,3'-(ethane-1,2-diyl)bis(2-(pyridin-3-yl)thiazolidin-4-one)

Guidance literature:: In benzene; at 5 - 10 ℃; for 0.25h;
DOI:10.1002/jhet.5570430228

Reference yield:

: 500-22-1
3-pyridinecarboxaldehyde

: 205688-81-9,131420-44-5
3,3'-(ethane-1,2-diyl)bis(2-(pyridin-3-yl)thiazolidin-4-one)

Guidance literature:: Multi-step reaction with 2 steps

1: 100 percent / ethanol / Heating

2: 40 percent / benzene / 0.25 h / 5 - 10 °C

In ethanol; benzene;
DOI:10.1002/jhet.5570430228