N-(4-chlorophenyl)-7H-purin-6-amine

Base Information

Chemical Name:N-(4-chlorophenyl)-7H-purin-6-amine
CAS No.:5450-44-2
Molecular Formula:C11H8ClN5
Molecular Weight:245.671
Hs Code.:
NSC Number:11613
ChEMBL ID:CHEMBL4202442

Synonyms:N-(4-chlorophenyl)-7H-purin-6-amine;Oprea1_303954;SCHEMBL4923801;CHEMBL4202442;NSC11613;NSC-11613;STK871923;AKOS003612348;AKOS005613917;SR-01000007283;SR-01000007283-1;Z1101445240

Suppliers and Price of N-(4-chlorophenyl)-7H-purin-6-amine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 5 raw suppliers

Chemical Property of N-(4-chlorophenyl)-7H-purin-6-amine

Chemical Property:

Vapor Pressure:3.95E-06mmHg at 25°C
Boiling Point:384.9°Cat760mmHg
Flash Point:186.6°C
Density:1.56g/cm³
XLogP3:2.8
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:2
Exact Mass:245.0468230
Heavy Atom Count:17
Complexity:256

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC(=CC=C1NC2=NC=NC3=C2NC=N3)Cl

Technology Process of N-(4-chlorophenyl)-7H-purin-6-amine

There total 5 articles about N-(4-chlorophenyl)-7H-purin-6-amine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 75.0%

: 106-47-8
4-chloro-aniline

: 87-42-3
6-chloropurine

: 5450-44-2
N-(4-chlorophenyl)-9H-purin-6-amine

Guidance literature:: In tetrahydrofuran; at 100 ℃; Microwave irradiation; Sealed tube;
DOI:10.1021/acs.jmedchem.1c01942

Reference yield: 73.9%

: 5450-44-2
N-(4-chlorophenyl)-9H-purin-6-amine

Guidance literature:: With triethylamine; In butan-1-ol; at 110 ℃; for 5h;

Reference yield:

: 50-44-2
6H-purine-6-thione

: 5450-44-2
(4-chloro-phenyl)-(7⁽⁹⁾H-purin-6-yl)-amine

Guidance literature:: Multi-step reaction with 2 steps

1: dimethyl sulfate; aq. NaOH solution

With sodium hydroxide; dimethyl sulfate;
DOI:10.1021/ja01122a037