1,1,3-Trichloro-1,2,2-trifluoropropane

Base Information

• Chemical Name: 1,1,3-Trichloro-1,2,2-trifluoropropane
• CAS No.: 421-99-8
• Molecular Formula: C₃H₂Cl₃F₃
• Molecular Weight: 201.403
• Hs Code.: 2903791090
• DSSTox Substance ID: DTXSID80564115
• Wikidata: Q82448707
• Mol file: 421-99-8.mol

Synonyms:1,1,3-TRICHLORO-1,2,2-TRIFLUOROPROPANE;421-99-8;HCFC-233cb;SCHEMBL1992059;DTXSID80564115;CPHFUGPCSJJMOI-UHFFFAOYSA-N

Chemical Property of 1,1,3-Trichloro-1,2,2-trifluoropropane

Chemical Property:

• Refractive Index: 1.3665 (estimate)
• Boiling Point: 69.16°C (rough estimate)
• PSA: 0.00000
• Density: 1.4317 (estimate)
• LogP: 2.96140
• XLogP3: 3.1
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 2
• Exact Mass: 199.917418
• Heavy Atom Count: 9
• Complexity: 103

Purity/Quality:

98%min ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C(C(C(F)(Cl)Cl)(F)F)Cl

Technology Process of 1,1,3-Trichloro-1,2,2-trifluoropropane

There total 5 articles about 1,1,3-Trichloro-1,2,2-trifluoropropane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 29.0%

1,1,3,3-tetrachloro-1,2,2-trifluoropropane (422-52-6,134237-37-9) → 1,1-dichloro-2,2-difluoropropane (1112-01-2) + 1,1-dichloro-1,2,2-trifluoropropane (7125-99-7) + 1,1,3-trichloro-1,2,2-trifluoropropane (421-99-8) + 1,1,3-trichloro-2,2,3-trifluoropropane (131221-36-8)

Guidance literature:

With hydrogen; platinum on activated charcoal; at 120 ℃; Further byproducts given;

DOI:10.1016/S0022-1139(00)82839-0

Reference yield: 29.0%

1,1,3,3-tetrachloro-1,2,2-trifluoropropane (422-52-6,134237-37-9) → 1,1-dichloro-1,2,2-trifluoropropane (7125-99-7) + 1,1,3-trichloro-1,2,2-trifluoropropane (421-99-8) + 1,3-dichloro-1,2,2-trifluoropropane (67406-68-2) + 1,1,3-trichloro-2,2,3-trifluoropropane (131221-36-8)

Guidance literature:

With hydrogen; platinum on activated charcoal; at 120 ℃; Further byproducts given;

DOI:10.1016/S0022-1139(00)82839-0

Reference yield: 29.0%

1,1,3,3-tetrachloro-1,2,2-trifluoropropane (422-52-6,134237-37-9) → 1,1-dichloro-1,2,2-trifluoropropane (7125-99-7) + 1,1,3-trichloro-1,2,2-trifluoropropane (421-99-8) + 1,1-dichloro-2,2,3-trifluoropropane (70192-70-0) + 1,1,3-trichloro-2,2,3-trifluoropropane (131221-36-8)

Guidance literature:

With hydrogen; platinum on activated charcoal; at 120 ℃; Further byproducts given;

DOI:10.1016/S0022-1139(00)82839-0

upstream raw materials:

1,1,1,3-tetrachloro-2,2-difluoropropane

1,1,3,3-tetrachloro-1,2,2-trifluoropropane

antimony(III) fluoride

chlorine

Downstream raw materials:

1,1-dichloro-1,2,2-trifluoropropane

1,1,2-trifluoropropane

1,3-dichloro-1,2,2-trifluoropropane

1-chloro-1,2,2-trifluoropropane