[1,2,4]Triazolo[4,3-b]pyridazin-8-amine

Base Information

Chemical Name:[1,2,4]Triazolo[4,3-b]pyridazin-8-amine
CAS No.:6583-39-7
Molecular Formula:C₅H₅N₅
Molecular Weight:135.128
Hs Code.:
NSC Number:75294
DSSTox Substance ID:DTXSID50984321
Wikidata:Q82971510

Synonyms:[1,2,4]triazolo[4,3-b]pyridazin-8-amine;6583-39-7;NSC75294;SCHEMBL18878946;DTXSID50984321;CCG-40350;NSC-75294;AKOS006337990;CS-0079776;D74084

Suppliers and Price of [1,2,4]Triazolo[4,3-b]pyridazin-8-amine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 6 raw suppliers

Chemical Property of [1,2,4]Triazolo[4,3-b]pyridazin-8-amine

Chemical Property:

Boiling Point:°Cat760mmHg
Flash Point:°C
Density:1.74g/cm³
XLogP3:-0.9
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:0
Exact Mass:135.05449518
Heavy Atom Count:10
Complexity:127

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=C(C2=NN=CN2N=C1)N

Technology Process of [1,2,4]Triazolo[4,3-b]pyridazin-8-amine

There total 2 articles about [1,2,4]Triazolo[4,3-b]pyridazin-8-amine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

: 6698-57-3
6-chloro-1,2,4-triazolo<4,3-b>pyridazin-8-amine

: 6583-39-7
[1,2,4]triazolo[4,3-b]pyridazin-8-ylamine

Guidance literature:: With palladium 10% on activated carbon; hydrogen; N-ethyl-N,N-diisopropylamine; In ethanol; at 20 ℃; for 72h; under 2068.65 Torr; Inert atmosphere;
DOI:10.1021/jm401356t

Reference yield:

: 6583-39-7
[1,2,4]triazolo[4,3-b]pyridazin-8-ylamine

Guidance literature:: 7-Chlor-8-amino-s-triazolo <4,3-b> pyridazin/NaOH/H2O/A., H2/Pd-C;

Reference yield:

: 6583-39-7
[1,2,4]triazolo[4,3-b]pyridazin-8-ylamine

: 1569870-23-0
[2-(4-methoxy-phenyl)-ethyl]-[1,2,4]triazolo[4,3-b]pyridazin-8-yl-amine

Guidance literature:: Multi-step reaction with 2 steps

1: isopentyl nitrite; diiodomethane / acetonitrile / 1 h / Reflux; Inert atmosphere

2: potassium carbonate / N,N-dimethyl-formamide / 16 h / 105 °C / Inert atmosphere

With diiodomethane; potassium carbonate; isopentyl nitrite; In N,N-dimethyl-formamide; acetonitrile;
DOI:10.1021/jm401356t