5-(2-Ethoxy-phenylamino)-[1,3,4]thiadiazole-2-thiol

Base Information

• Chemical Name: 5-(2-Ethoxy-phenylamino)-[1,3,4]thiadiazole-2-thiol
• CAS No.: 52494-34-5
• Molecular Formula: C₁₀H₁₁N₃OS₂
• Molecular Weight: 253.349
• Hs Code.: 2934999090
• DSSTox Substance ID: DTXSID90351295
• Wikidata: Q82127602
• Mol file: 52494-34-5.mol

Synonyms:52494-34-5;5-(2-Ethoxy-phenylamino)-[1,3,4]thiadiazole-2-thiol;5-(2-ethoxyanilino)-3H-1,3,4-thiadiazole-2-thione;5-((2-Ethoxyphenyl)amino)-1,3,4-thiadiazole-2-thiol;5-[(2-ethoxyphenyl)amino]-1,3,4-thiadiazole-2-thiol;Oprea1_660126;DTXSID90351295;CCG-49467;AKOS000116426;CS-0219201;EN300-03398;AB00712658-01;SR-01000638918-1;Z56828377;5-(2-Ethoxyanilino)-1,3,4-thiadiazole-2(3H)-thione;5-[(2-Ethoxyphenyl)amino]-1,3,4-thiadiazole-2(3H)-thione

Chemical Property of 5-(2-Ethoxy-phenylamino)-[1,3,4]thiadiazole-2-thiol

Chemical Property:

• Vapor Pressure: 1.32E-05mmHg at 25°C
• Boiling Point: 367.9°Cat760mmHg
• Flash Point: 176.3°C
• PSA: 117.31000
• Density: 1.41g/cm³
• LogP: 2.39100
• XLogP3: 2.6
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 4
• Exact Mass: 253.03435433
• Heavy Atom Count: 16
• Complexity: 296

Purity/Quality:

99% ^*data from raw suppliers

5-((2-Ethoxyphenyl)amino)-1,3,4-thiadiazole-2-thiol 97% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: CCOC1=CC=CC=C1NC2=NNC(=S)S2

Technology Process of 5-(2-Ethoxy-phenylamino)-[1,3,4]thiadiazole-2-thiol

There total 1 articles about 5-(2-Ethoxy-phenylamino)-[1,3,4]thiadiazole-2-thiol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

carbon disulfide (75-15-0,12122-00-8) + 4-(2-ethoxyphenyl)-3-thiosemicarbazide (64374-51-2) → 5-(2-ethoxy-anilino)-3H-[1,3,4]thiadiazole-2-thione (52494-34-5)

Guidance literature:

In ethanol; Heating;

Reference yield: 70.0%

5-(2-ethoxy-anilino)-3H-[1,3,4]thiadiazole-2-thione (52494-34-5) + (2-chloroacetyl)urea (4791-21-3) → {2-[5-(2-Ethoxy-phenylamino)-[1,3,4]thiadiazol-2-ylsulfanyl]-acetyl}-urea

Guidance literature:

With sodium hydroxide; In methanol; for 3h; Heating;

Reference yield:

5-(2-ethoxy-anilino)-3H-[1,3,4]thiadiazole-2-thione (52494-34-5) → [5-(2-ethoxy-anilino)-[1,3,4]thiadiazol-2-ylsulfanyl]-acetic acid hydrazide (52494-27-6)

Guidance literature:

Multi-step reaction with 2 steps

1: NaOH / ethanol

2: N₂H₄*H₂O / ethanol

With sodium hydroxide; hydrazine hydrate; In ethanol;

upstream raw materials:

carbon disulfide

4-(2-ethoxyphenyl)-3-thiosemicarbazide

Downstream raw materials:

(2-ethoxy-phenyl)-(5-ethylsulfanyl-[1,3,4]thiadiazol-2-yl)-amine

[5-(2-ethoxy-anilino)-[1,3,4]thiadiazol-2-ylsulfanyl]-acetic acid

[5-(2-ethoxy-anilino)-[1,3,4]thiadiazol-2-ylsulfanyl]-acetic acid hydrazide

1-{[5-(2-ethoxy-anilino)-[1,3,4]thiadiazol-2-ylsulfanyl]-acetyl}-4-phenyl-semicarbazide

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 52494-34-5 5-(2-ETHOXY-PHENYLAMINO)-[1,3,4]THIADIAZOLE-2-THIOL

Send

Send

Metric Ton KG G Pound L ML

Send

Send