4791-21-3

Basic information

• Product Name: chloroacetyl-ure
• Synonyms: chloroacetyl-ure;chloroacetylurea;n-(aminocarbonyl)-2-chloro-acetamid;N-aminocarbonyl-2-chloro-ethanamide;N-carbamoyl-2-chloroacetamide;N-carbamoyl-2-chloro-acetamide;AcetaMide,N-(aMinocarbonyl)-2-chloro-
• CAS NO: 4791-21-3
• Molecular Formula: C₃H₅ClN₂O₂
• Molecular Weight: 136.537
• Mol File: 4791-21-3.mol

Chemical Properties

• Boiling Point: °Cat760mmHg
• Flash Point: °C
• Appearance: /
• Density: 1.419g/cm³
• Refractive Index: 1.493
• CAS DataBase Reference: chloroacetyl-ure(CAS DataBase Reference)
• NIST Chemistry Reference: chloroacetyl-ure(4791-21-3)
• EPA Substance Registry System: chloroacetyl-ure(4791-21-3)

Safety Data

• Hazardous Substances Data: 4791-21-3(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
Chloroacetyl-urea is used as an intermediate in the production of pharmaceutical drugs. Its chemical properties allow it to be a key component in the synthesis of various medications, contributing to the development of new and effective treatments.
Used in Agrochemical Industry:
Chloroacetyl-urea is utilized as an intermediate in the formulation of pesticides and herbicides. Its ability to react with other compounds makes it a valuable component in creating effective agricultural chemicals that protect crops and enhance yields.
Used in Chemical Industry:
Chloroacetyl-urea is employed in various chemical processes due to its versatility. It serves as a crucial intermediate in the synthesis of a wide range of organic compounds, contributing to the advancement of the chemical industry and the development of new products.

InChI:InChI=1/C3H5ClN2O2/c4-1-2(7)6-3(5)8/h1H2,(H3,5,6,7,8)

Upstream product

• 79-11-8 chloroacetic acid 
• 57-13-6 urea 
• 79-04-9 chloroacetyl chloride 
• 4461-30-7 2-chloroacetylisocyanate 

Downstream Products

• 28788-22-9 (N,N-dibutyl-glycyl)-urea 
• 69124-33-0 <<8-<5-(4-fluorophenyl)-2-pentyl>-10-hydroxy-5,5-dimethyl-1,2,3,4-tetrahydro-5H-<1>benzopyrano<4,3-c>pyridin-2-yl>acetyl>urea 
• 5827-10-1 (dimethoxythiophosphorylsulfanyl-acetyl)-urea 
• 124-38-9 carbon dioxide 
• 556-90-1 pseudothiohydantoin 
• 626-36-8 ethyl allophanate 
• 61893-09-2 1-ethylimidazolidine-2,4-dione 
• 92852-04-5 dithiophosphoric acid S-allophanoylmethyl ester-O,O'-diphenyl ester 

Relevant articles and documents

11,13-MODIFIED SAXITOXINS FOR THE TREATMENT OF PAIN

Provided herein are compounds, pharmaceutical compositions comprising the compounds, methods of preparing the compounds, and methods of using the compounds and compositions in treating conditions associated with voltage-gated sodium channel function where the compounds are 11,13-modified saxitoxins according to Formula (I): where R4, R4a, R7, R7a, and X2 are as described herein.

Anti-inflammatory agents

Disclosed are novel compounds that are useful in regulating the expression of interleukin-6 (IL-6) and/or vascular cell adhesion molecule-1 (VCAM-1), and their use in the treatment and/or prevention of cardiovascular and inflammatory diseases and related disease states, such as, for example, atherosclerosis, asthma, arthritis, cancer, multiple sclerosis, psoriasis, and inflammatory bowel diseases, and autoimmune disease(s). Also, disclosed are compositions comprising the novel compounds, as well as methods for their preparation.

TREATMENT OF DISEASES BY EPIGENETIC REGULATION

The present disclosure provides non-naturally occurring polyphenol compounds that inhibit the bromodomain and extra terminal domain (BET) proteins. The disclosed compositions and methods can be used for treatment and prevention of diseases or disorders that are susceptible to administration of a BET inhibitor.

Solid-phase synthesis of disubstituted N -acylureas from resin-bound ureas and acyl chlorides

Acylureas (ureides) are valued for their important biological activities. Whereas cyclic acylureas have frequently been the object of solid-phase chemistry, only few reports have focused on the solid-supported preparation of acyclic representatives. We have prepared different types of acylureas on Rink amide resin in three or four steps. The products are either N-acylated (9, 18), N-acylated-N′-alkylated (10, 19), or N-acylated-N-alkylated (22). Characteristic NMR parameters of isomeric acylureas 10, 19, and 22 are discussed.

Novel peptidomimetics of the antifungal cyclic peptide rhodopeptin: Synthesis of mimetics and their antifungal activity

(matrix presented) Novel peptidomimetics of the antifungal cyclic peptide Rhodopeptin were synthesized. As with the cyclic peptides, the presence of all three Rhodopeptin side chains was found to be indispensable for peptidomimetic activity. We discovered