cholestan-3-amine

Base Information

• Chemical Name: cholestan-3-amine
• CAS No.: 5457-79-4
• Molecular Formula: C27H49N
• Molecular Weight: 387.6847
• Mol file: 5457-79-4.mol

Synonyms:

Chemical Property of cholestan-3-amine

Chemical Property:

• Vapor Pressure: 9.02E-09mmHg at 25°C
• Boiling Point: 463.5°Cat760mmHg
• Flash Point: 228.3°C
• Density: 0.93g/cm³

Purity/Quality:

99%min ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of cholestan-3-amine

There total 3 articles about cholestan-3-amine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

3α-amino-5α-cholestane (2206-20-4) → 3α-amino-5α-cholestane hydrochloride (5457-79-4)

Guidance literature:

With hydrogenchloride; In diethyl ether;

Reference yield:

Cholestanol (80-97-7) → 3α-amino-5α-cholestane hydrochloride (5457-79-4)

Guidance literature:

Multi-step reaction with 3 steps

1: triphenylphosphine; diphenyl phosphoryl azide; di-isopropyl azodicarboxylate / tetrahydrofuran

2: lithium aluminium tetrahydride / tetrahydrofuran / Reflux

3: hydrogenchloride / diethyl ether

With hydrogenchloride; lithium aluminium tetrahydride; di-isopropyl azodicarboxylate; diphenyl phosphoryl azide; triphenylphosphine; In tetrahydrofuran; diethyl ether;

Reference yield:

3α-azido-5α-cholestane (15067-20-6) → 3α-amino-5α-cholestane hydrochloride (5457-79-4)

Guidance literature:

Multi-step reaction with 2 steps

1: lithium aluminium tetrahydride / tetrahydrofuran / Reflux

2: hydrogenchloride / diethyl ether

With hydrogenchloride; lithium aluminium tetrahydride; In tetrahydrofuran; diethyl ether;

upstream raw materials:

3α-amino-5α-cholestane

Cholestanol

3α-azido-5α-cholestane

Downstream raw materials:

N-(5α-cholestan-3α-yl)-3,3-bis(3-chloro-4-methoxy-5-methoxycarbonylphenyl)-2-propenamine

Refernces