Sirtinol

Base Information

Chemical Name:Sirtinol
CAS No.:410536-97-9
Molecular Formula:C26H22N2O2
Molecular Weight:394.473
Hs Code.:2925290090
Nikkaji Number:J1.625.763J
Wikidata:Q27140353,Q27215793
Metabolomics Workbench ID:66283
ChEMBL ID:CHEMBL380797
Mol file:410536-97-9.mol

Synonyms:sirtinol

Suppliers and Price of Sirtinol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Usbiological
Sirtinol
5mg
$ 462.00

Usbiological
Sirtinol
10mg
$ 438.00

Usbiological
Sirtinol
1mg
$ 273.00

Usbiological
Sirtinol
10mg
$ 382.00

TRC
Sirtinol
5mg
$ 65.00

TRC
Sirtinol
50mg
$ 290.00

TRC
Sirtinol
25mg
$ 205.00

Tocris
Sirtinol ≥98%(HPLC)
10
$ 191.00

Tocris
Sirtinol ≥98%(HPLC)
50
$ 781.00

SynChem
{2-[(2-Hydroxynaphthalen-1-ylmethylene)amino]}-N-(1-phenethyl)benzamide (Sirtinol) 97+%
10 g
$ 1250.00

Total 36 raw suppliers

Chemical Property of Sirtinol

Chemical Property:

Vapor Pressure:8.88E-17mmHg at 25°C
Melting Point:119-120℃
Boiling Point:650°Cat760mmHg
PKA:7.85±0.50(Predicted)
Flash Point:211.4°C
PSA：61.69000
Density:1.276g/cm³
LogP:6.17790
Storage Temp.:−20°C
Solubility.:Soluble in DMSO (up to 30 mg/ml).
Water Solubility.:Soluble in water, DMSO and methanol
XLogP3:5.3
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:5
Exact Mass:394.168127949
Heavy Atom Count:30
Complexity:586

Purity/Quality:

99%, ^*data from raw suppliers

Sirtinol ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C1=CC=CC=C1)NC(=O)C2=CC=CC=C2N=CC3=C(C=CC4=CC=CC=C43)O
Description Sirtinol (410536-97-9) is an inhibitor of sirtuin family enzymes including human SIRT1 (IC50=60 μM), human SIRT2 (IC50=58 μM), and yeast Sir2 (IC50=48 μM) with no inhibition of human HDAC1. Active in vivo and in purified enzyme studies. Cell permeable.
Uses Sirtinol is a known inhibitor of the NAD+-Dependent Protein Desuccinylase and Demalonylase Sirt5 and exhibits anticancer properties. Sirtinol is a cell permeable specific inhibitor of sirtuin NAD-dependant deacetylases

Technology Process of Sirtinol

There total 2 articles about Sirtinol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%