1-(2-Hydroxyphenyl)piperazine

Base Information

Chemical Name:1-(2-Hydroxyphenyl)piperazine
CAS No.:1011-17-2
Molecular Formula:C10H14N2O
Molecular Weight:178.234
Hs Code.:29339900
European Community (EC) Number:213-782-5
UNII:M3A5WD54AW
DSSTox Substance ID:DTXSID90143733
Nikkaji Number:J217.129E
Wikidata:Q72481104
ChEMBL ID:CHEMBL266250
Mol file:1011-17-2.mol

Synonyms:1011-17-2;1-(2-Hydroxyphenyl)piperazine;2-(piperazin-1-yl)phenol;2-(1-Piperazino)phenol;2-(1-piperazinyl)phenol;2-piperazin-1-ylphenol;Phenol, 2-(1-piperazinyl)-;o-(1-Piperazinyl)phenol;2-Piperazin-1-yl-phenol;n-(2-hydroxyphenyl)piperazine;1-(2-Hydroxyphenyl)-piperazine;EINECS 213-782-5;MFCD00190246;CHEMBL266250;2-Piperazinophenol;D02OZB;2-(piperazine-1-yl)phenol;M3A5WD54AW;Oprea1_446736;Phenol,2-(1-piperazinyl)-;SCHEMBL531748;4-(2-hydroxyphenyl)-piperazine;N-(2-Hydroxyphenyl)piperprazine;1-(2-hydroxy-phenyl)-piperazine;DTXSID90143733;AMY17894;BDBM50017456;STL186168;1-(2-Hydroxyphenyl)piperazine, 97%;AKOS000119523;FS-1232;AC-23077;FT-0629153;EN300-20404;H10665;AE-562/41428846;F2190-0532;Z104478056

Suppliers and Price of 1-(2-Hydroxyphenyl)piperazine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
2-(Piperazin-1-yl)phenol
50mg
$ 60.00

TRC
2-(Piperazin-1-yl)phenol
200mg
$ 75.00

TRC
2-(Piperazin-1-yl)phenol
25mg
$ 45.00

SynQuest Laboratories
1-(2-Hydroxyphenyl)piperazine 98.0%
10 g
$ 80.00

SynQuest Laboratories
1-(2-Hydroxyphenyl)piperazine 98.0%
250 g
$ 760.00

SynQuest Laboratories
1-(2-Hydroxyphenyl)piperazine 98.0%
50 g
$ 200.00

Medical Isotopes, Inc.
2-(Piperazin-1-yl)phenol 98%
10 g
$ 358.00

Matrix Scientific
2-(1-Piperazino)phenol 95%+
2.500g
$ 215.00

Matrix Scientific
2-(1-Piperazino)phenol 95%+
5g
$ 323.00

Matrix Scientific
2-(1-Piperazino)phenol 95%+
1g
$ 101.00

Total 63 raw suppliers

Chemical Property of 1-(2-Hydroxyphenyl)piperazine

Chemical Property:

Appearance/Colour:brown-pink to brown powder and chunks
Vapor Pressure:0.000101mmHg at 25°C
Melting Point:125-129 °C
Boiling Point:328.2 °C at 760 mmHg
PKA:11.25±0.35(Predicted)
Flash Point:152.3 °C
PSA：35.50000
Density:1.141 g/cm³
LogP:1.19560
XLogP3:1
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:1
Exact Mass:178.110613074
Heavy Atom Count:13
Complexity:157

Purity/Quality:

99%, ^*data from raw suppliers

2-(Piperazin-1-yl)phenol ^*data from reagent suppliers

Safty Information:

Pictogram(s): T, Xi
Hazard Codes:T,Xi
Statements: 25-36/37/38
Safety Statements: 26-37/39-45

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

Canonical SMILES:C1CN(CCN1)C2=CC=CC=C2O
Uses 2-(Piperazin-1-yl)phenol is used in preparation of substituted imidazoles and oxazoles in the treatment of cancers and other medical conditions.

Technology Process of 1-(2-Hydroxyphenyl)piperazine

There total 5 articles about 1-(2-Hydroxyphenyl)piperazine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 57.0%