9-Acetyl-4-((dimethylamino)methyl)-2,3,4,9-tetrahydrothiopyrano(2,3-b)indole hydrochloride

Base Information

• Chemical Name: 9-Acetyl-4-((dimethylamino)methyl)-2,3,4,9-tetrahydrothiopyrano(2,3-b)indole hydrochloride
• CAS No.: 73424-77-8
• Molecular Formula: C₁₆H₂₀N₂OS*ClH
• Molecular Weight: 324.875
• DSSTox Substance ID: DTXSID80994150
• Mol file: 73424-77-8.mol

Synonyms:9-Acetyl-4-((dimethylamino)methyl)-2,3,4,9-tetrahydrothiopyrano(2,3-b)indole hydrochloride;9-Acetyl-4-(N,N-dimethylaminomethyl)-2,3,4,9-tetrahydrothiopyrano(2,3-b)indole hydrochloride;Thiopyrano(2,3-b)indole-4-methylamine, 2,3,4,9-tetrahydro-9-acetyl-N,N-dimethyl-, HCl;73424-77-8;Thiopyrano(2,3-b)indole, 2,3,4,9-tetrahydro-9-acetyl-4-((dimethylamino)methyl)-, monohydrochloride;C16H20N2OS.ClH;DTXSID80994150;LS-153270;1-[4-{[Bis(methylsulfanyl)amino]methyl}-3,4-dihydropyrano[2,3-b]indol-9(2H)-yl]ethan-1-one--hydrogen chloride (1/1)

Chemical Property of 9-Acetyl-4-((dimethylamino)methyl)-2,3,4,9-tetrahydrothiopyrano(2,3-b)indole hydrochloride

Chemical Property:

• Vapor Pressure: 1.76E-09mmHg at 25°C
• Boiling Point: 482.9°Cat760mmHg
• Flash Point: 245.9°C
• Density: g/cm³
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 5
• Rotatable Bond Count: 4
• Exact Mass: 372.0732980
• Heavy Atom Count: 23
• Complexity: 406

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: CC(=O)N1C2=CC=CC=C2C3=C1OCCC3CN(SC)SC.Cl

Technology Process of 9-Acetyl-4-((dimethylamino)methyl)-2,3,4,9-tetrahydrothiopyrano(2,3-b)indole hydrochloride

There total 1 articles about 9-Acetyl-4-((dimethylamino)methyl)-2,3,4,9-tetrahydrothiopyrano(2,3-b)indole hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

acetyl chloride (75-36-5) + 4-(N,N-dimethylaminomethyl)-2,3,4,9-tetrahydrothiopyrano<2,3-b>indole (73425-59-9) → 9-acetyl-4-(N,N-dimethylaminomethyl)-2,3,4,9-tetrahydrothiopyrano<2,3-b>indole hydrochloride (73424-77-8)

Guidance literature:

With hydrogenchloride; sodium hydride; Yield given. Multistep reaction; 1) oil, DMF, RT, 2 h; 2) oil, DMF, RT, 1 h;

DOI:10.1248/cpb.32.877

upstream raw materials:

acetyl chloride

4-(N,N-dimethylaminomethyl)-2,3,4,9-tetrahydrothiopyrano<2,3-b>indole

Refernces