Chlorproguanil

Base Information

Chemical Name:Chlorproguanil
CAS No.:537-21-3
Molecular Formula:C11H16Cl3N5
Molecular Weight:288.18
Hs Code.:
European Community (EC) Number:208-660-3
UNII:8O3249M729
DSSTox Substance ID:DTXSID5022807
Wikipedia:Chlorproguanil
NCI Thesaurus Code:C79941
ChEMBL ID:CHEMBL1213553
Mol file:537-21-3.mol

Synonyms:chlorproguanil;lapudrine;mono-HCl of chlorproguanil;unspecified HCl of chlorproguanil

Suppliers and Price of Chlorproguanil

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
CHLORPROGUANIL 95.00%
500MG
$ 1963.50

American Custom Chemicals Corporation
CHLORPROGUANIL 95.00%
50MG
$ 750.75

Total 14 raw suppliers

Chemical Property of Chlorproguanil

Chemical Property:

Melting Point:120-121 °C
Boiling Point:426.9°Cat760mmHg
PKA:10.77±0.10(Predicted)
Flash Point:212°C
PSA：83.79000
Density:1.4g/cm³
LogP:3.91670
XLogP3:3
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:4
Exact Mass:287.0704509
Heavy Atom Count:18
Complexity:329

Purity/Quality:

97% ^*data from raw suppliers

CHLORPROGUANIL 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C)N=C(N)N=C(N)NC1=CC(=C(C=C1)Cl)Cl
Isomeric SMILES:CC(C)N=C(N)/N=C(\N)/NC1=CC(=C(C=C1)Cl)Cl
Uses PROGUANIL HYDROCHLORIDE is an antimalarial agent used in combination with Dapsone (D193250).
Clinical Use Malaria chemoprophylaxis
Drug interactions Potentially hazardous interactions with other drugs Anticoagulants: effect of warfarin possibly enhanced. Antimalarials: avoid concomitant use with artemether/lumefantrine; increased antifolate effect with pyrimethamine.

Technology Process of Chlorproguanil

There total 8 articles about Chlorproguanil which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: