trans-1,4-Cyclohexanedicarboxybic acid

Base Information

• Chemical Name: trans-1,4-Cyclohexanedicarboxybic acid
• CAS No.: 619-82-9
• Molecular Formula: C8H12 O4
• Molecular Weight: 172.181
• Hs Code.: 2917209090
• Mol file: 619-82-9.mol

Synonyms:trans-1,4-Cyclohexane-1,4-dicarboxylicacid; trans-1,4-Cyclohexanedicarboxylic acid; trans-1,4-Cyclohexyldicarboxylicacid; trans-4-Carboxycyclohexanecarboxylic acid; trans-Hexahydroterephthalicacid

Chemical Property of trans-1,4-Cyclohexanedicarboxybic acid

Chemical Property:

• Appearance/Colour: White crystal
• Melting Point: >300 °C(lit.)
• Refractive Index: 1.4795 (estimate)
• Boiling Point: 384.1 °C at 760 mmHg
• PKA: pK1:4.18 ;pK2:5.42 (16°C)
• Flash Point: 200.3 °C
• PSA: 74.60000
• Density: 1.314 g/cm³
• LogP: 0.96200
• Storage Temp.: Sealed in dry,Room Temperature
• Water Solubility.: Soluble in hot methanol (almost transparency), ethanol, acetone. Slightly soluble in ether and water

Purity/Quality:

99% ^*data from raw suppliers

trans-1,4-Cyclohexanedicarboxylic acid ^*data from reagent suppliers

Safty Information:

• Statements: 36/37/38
• Safety Statements: 26-36/37/39-24/25

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Uses: It is a pharmaceutical intermediate.

Technology Process of trans-1,4-Cyclohexanedicarboxybic acid

There total 49 articles about trans-1,4-Cyclohexanedicarboxybic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

C14H24O6 → trans-hexahydroterephthalic acid (619-82-9)

Guidance literature:

With trifluoroacetic acid; In tetrahydrofuran; at 50 ℃; for 4h;

Reference yield: 99.0%

C16H28O8 → trans-hexahydroterephthalic acid (619-82-9)

Guidance literature:

With trifluoroacetic acid; In tetrahydrofuran; at 50 ℃; for 3.5h;

Reference yield: 96.0%

dimethyl 1,4-cyclohexane dicarboxylate (94-60-0) → cyclohexane-1,4-dicarboxylic acid (619-81-8,619-82-9,1076-97-7)

Guidance literature:

With sulfuric acid; In water; at 100 ℃; for 3h; Reagent/catalyst; Temperature;

upstream raw materials:

iodomethane-d3

bis-1,4-(hydroxymethyl)cyclohexane

ethyl iodide

dimethyl 1,4-cyclohexane dicarboxylate

Downstream raw materials:

trans-1,4-di-tert-butylcyclohexane

trans-4-(methoxycarbonyl)cyclohexanecarboxylic acid

dimethyl 1,4-cyclohexanedicarboxylate

trans-1,4-cyclohexanedicarboxylic acid dichloride

Refernces

• 1、 Ahamad, Tansir,Kankala, Ranjith Kumar,Mao, Cong,Matsagar, Babasaheb M.,Wu, Kevin C.-W.,Yang, Yucheng,Zhang, Xueqin,Zheng, Jingwei. "Highly-efficient Ru/Al-SBA-15 catalysts with strong Lewis acid sites for the water-assisted hydrogenation of: P -phthalic acid". . p. 2443 - 2451. Retrieved 2020/05/14.
• 2、 -. "METHOD FOR PRODUCING 1,4-DICYANOCYCLOHEXANE, 1,4-BIS(AMINOMETHYL)CYCLOHEXANE AND 1,4-CYCLOHEXANEDICARBOXYLIC ACID". . . Retrieved 2019/08/02.