N-(2-Methylphenyl)-2-methylbenzenamine

Base Information

• Chemical Name: N-(2-Methylphenyl)-2-methylbenzenamine
• CAS No.: 617-00-5
• Molecular Formula: C14H15N
• Molecular Weight: 197.28
• Mol file: 617-00-5.mol

Synonyms:di-ortho-tolylamine;Di-o-tolylamine;Benzenamine, 2-methyl-N-(2-methylphenyl)-;1,1'-dimethyldiphenylamine;2-methyl-N-(2-methylphenyl)aniline;

Chemical Property of N-(2-Methylphenyl)-2-methylbenzenamine

Chemical Property:

• Vapor Pressure: 0.000555mmHg at 25°C
• Melting Point: 52.5°C
• Refractive Index: 1.6095 (estimate)
• Boiling Point: 311.7°Cat760mmHg
• PKA: 0.53±0.40(Predicted)
• Flash Point: 147.1°C
• PSA: 12.03000
• Density: 1.049g/cm³
• LogP: 4.12000
• Storage Temp.: Keep in dark place,Inert atmosphere,Room temperature

Purity/Quality:

99%, ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of N-(2-Methylphenyl)-2-methylbenzenamine

There total 29 articles about N-(2-Methylphenyl)-2-methylbenzenamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

2-methylchlorobenzene (95-49-8) + o-toluidine (95-53-4) → 2,2'-dimethyldiphenylamine (617-00-5)

Guidance literature:

With C₂₈H₂₉Cl₂N₃OPd; potassium tert-butylate; In toluene; at 110 ℃; for 15h; Schlenk technique; Inert atmosphere;

DOI:10.1007/s11243-016-0048-1

Reference yield: 98.0%

1-chloro-3-methylbenzene (108-41-8) + o-toluidine (95-53-4) → 2,2'-dimethyldiphenylamine (617-00-5)

Guidance literature:

With bis{1,1’-dimethyl-3,3’-methylenediimidazoline-2,2’-diylidene}nickel(II) dibromide; potassium tert-butylate; In 1,4-dioxane; at 90 ℃; for 4h; Reagent/catalyst; Catalytic behavior; Inert atmosphere; Schlenk technique;

DOI:10.1016/j.jorganchem.2016.12.029

Reference yield: 95.0%

2-methylchlorobenzene (95-49-8) → 2,2'-dimethyldiphenylamine (617-00-5)

Guidance literature:

With lithium amide; tris(dibenzylideneacetone)dipalladium ⁽⁰⁾; johnphos; sodium t-butanolate; In toluene; at 80 ℃; for 19h;

DOI:10.1021/ol0166808

upstream raw materials:

2-methylchlorobenzene

2-methylphenyl bromide

N-(2-methylphenyl)acetamide

ortho-cresol

Downstream raw materials:

N,N-di-o-tolylthiourea

N-acetyl-2,2'-dimethyldiphenylamine