(2-((Chloroformyl)oxy)ethyl)triphenylphosphonium chloride

Base Information

• Chemical Name: (2-((Chloroformyl)oxy)ethyl)triphenylphosphonium chloride
• CAS No.: 61083-59-8
• Molecular Formula: C8H7 N3
• Molecular Weight: 405.26
• Hs Code.: 2931900090
• European Community (EC) Number: 262-582-4
• DSSTox Substance ID: DTXSID80976577
• Mol file: 61083-59-8.mol

Synonyms:61083-59-8;(2-((Chloroformyl)oxy)ethyl)triphenylphosphonium chloride;EINECS 262-582-4;[2-[(CHLOROFORMYL)OXY]ETHYL]TRIPHENYLPHOSPHONIUM CHLORIDE;C21H19ClO2P.Cl;C21-H19-Cl-O2-P.Cl;DTXSID80976577;(2-((Chlorocarbonyl)oxy)ethyl)triphenylphosphonium chloride;{2-[(Chlorocarbonyl)oxy]ethyl}(triphenyl)phosphanium chloride;2-(Triphenylphosphonio)ethyl chloroformate chloride, purum, >=98.0% (T)

Chemical Property of (2-((Chloroformyl)oxy)ethyl)triphenylphosphonium chloride

Chemical Property:

• Melting Point: ~130 °C (dec.)
• PSA: 13.59000
• LogP: 4.21930
• Storage Temp.: −20°C
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 7
• Exact Mass: 404.0499722
• Heavy Atom Count: 26
• Complexity: 365

Purity/Quality:

99% ^*data from raw suppliers

2-(TRIPHENYLPHOSPHONIO)ETHYL CHLOROFORMATE CHLORIDE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s): C
• Hazard Codes: C
• Statements: 34-36/37
• Safety Statements: 26-36/37/39-45

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Canonical SMILES: C1=CC=C(C=C1)[P+](CCOC(=O)Cl)(C2=CC=CC=C2)C3=CC=CC=C3.[Cl-]
• Uses: 2-(Triphenylphosphonio)ethyl Chloroformate Chloride plays a major role in the protection of amino and hydroxyl functional groups in peptide chemistry.

Technology Process of (2-((Chloroformyl)oxy)ethyl)triphenylphosphonium chloride

There total 2 articles about (2-((Chloroformyl)oxy)ethyl)triphenylphosphonium chloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

phosgene (75-44-5) + β-hydroxyethyltriphenylphosphonium chloride (23250-03-5) → Chlorameisensaeure-2-(triphenylphosphonioethyl)ester-chlorid (61083-59-8)

Guidance literature:

In chloroform;

Reference yield:

→ Chlorameisensaeure-2-(triphenylphosphonioethyl)ester-chlorid (61083-59-8)

Guidance literature:

(2-Hydroxyaethyl)triphenylphosphonium-chlorid, Phosgen;

Reference yield: 96.0%

Chlorameisensaeure-2-(triphenylphosphonioethyl)ester-chlorid (61083-59-8) + N-(Trimethylsilyl)asparaginsaeure-1-tert-butylester → N-<2-(Triphenylphosphonio)ethoxycarbonyl>asparaginsaeure-1-tert-butylester-chlorid (86088-19-9)

Guidance literature:

In chloroform; at -10 ℃; for 8h;

DOI:10.1002/jlac.198319830302

upstream raw materials:

phosgene

β-hydroxyethyltriphenylphosphonium chloride

Downstream raw materials:

[2-(4-Nitro-phenoxycarbonyloxy)-ethyl]-triphenyl-phosphonium; chloride

Peoc-Ala-OH

N-<2-(Triphenylphosphonio)ethoxycarbonyl>leucin-chlorid

Peoc-Phe-OH