Glycine, N-(N-(N-(N-(N-(3-hydroxy-2-methyl-1-oxoundecyl)-N-methyl-L-leucyl)-L-alloisoleucyl)-L-seryl)-L-allothreonyl)-, rho-lactone

Base Information

Chemical Name:Glycine, N-(N-(N-(N-(N-(3-hydroxy-2-methyl-1-oxoundecyl)-N-methyl-L-leucyl)-L-alloisoleucyl)-L-seryl)-L-allothreonyl)-, rho-lactone
CAS No.:69639-47-0
Molecular Formula:C₃₄H₆₁N₅O₉
Molecular Weight:683.886
Hs Code.:
DSSTox Substance ID:DTXSID70219900
Mol file:69639-47-0.mol

Synonyms:Antibiotic SF 1902A5;SF-1902A5;Glycine, N-(N-(N-(N-(N-(3-hydroxy-2-methyl-1-oxoundecyl)-N-methyl-L-leucyl)-L-alloisoleucyl)-L-seryl)-L-allothreonyl)-, rho-lactone;69639-47-0;DTXSID70219900;C34H63N5O10;LS-72698

Suppliers and Price of Glycine, N-(N-(N-(N-(N-(3-hydroxy-2-methyl-1-oxoundecyl)-N-methyl-L-leucyl)-L-alloisoleucyl)-L-seryl)-L-allothreonyl)-, rho-lactone

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Total 3 raw suppliers

Chemical Property of Glycine, N-(N-(N-(N-(N-(3-hydroxy-2-methyl-1-oxoundecyl)-N-methyl-L-leucyl)-L-alloisoleucyl)-L-seryl)-L-allothreonyl)-, rho-lactone

Chemical Property:

Vapor Pressure:0mmHg at 25°C
Boiling Point:937.5°Cat760mmHg
Flash Point:520.8°C
PSA：238.93000
Density:1.139g/cm³
LogP:3.71890
XLogP3:2.4
Hydrogen Bond Donor Count:7
Hydrogen Bond Acceptor Count:10
Rotatable Bond Count:25
Exact Mass:683.44692854
Heavy Atom Count:48
Complexity:1090

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCCCCCCCC(C(=C)C(=O)N(C)C(CC(C)C)(C=O)C(=O)CNC(=O)C(C(C)O)NC(=O)C(CO)NC(=O)C(C(C)CC)N)O
Isomeric SMILES:CCCCCCCC[C@H](C(=C)C(=O)N(C)[C@](CC(C)C)(C=O)C(=O)CNC(=O)[C@H]([C@H](C)O)NC(=O)[C@H](CO)NC(=O)[C@H]([C@H](C)CC)N)O

Technology Process of Glycine, N-(N-(N-(N-(N-(3-hydroxy-2-methyl-1-oxoundecyl)-N-methyl-L-leucyl)-L-alloisoleucyl)-L-seryl)-L-allothreonyl)-, rho-lactone

There total 11 articles about Glycine, N-(N-(N-(N-(N-(3-hydroxy-2-methyl-1-oxoundecyl)-N-methyl-L-leucyl)-L-alloisoleucyl)-L-seryl)-L-allothreonyl)-, rho-lactone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

: 540482-17-5
OBn-SF-1902 A₅

: 69639-47-0
SF-1902 A₅

Guidance literature:: With hydrogen; palladium dihydroxide; In methanol; at 20 ℃; for 5.5h;
DOI:10.1016/S0040-4020(03)00110-8

Reference yield: 81.0%

: 308279-80-3
O-benzyl globomycin

: 69639-47-0
SF-1902 A₅

Guidance literature:: With hydrogen; palladium(II) hydroxide; In methanol; for 6h;
DOI:10.1021/jo1025145

Reference yield:

: 124-19-6
nonan-1-al

: 69639-47-0
SF-1902 A₅

Guidance literature:: Multi-step reaction with 8 steps

1.1: dicyclohexylboron triflate; Et₃N / CH₂Cl₂; hexane / 1.5 h / -78 °C

1.2: 87 percent / CH₂Cl₂; hexane / 5 h / -78 - 0 °C

2.1: 90 percent / LiOH*H₂O / H₂O; tetrahydrofuran; methanol / 20 °C

3.1: 99 percent / Et₃N; diethylcyanophosphate / tetrahydrofuran / 0 - 20 °C

4.1: 82 percent / CSA; DMAP; DIC / CH₂Cl₂ / 20 °C

5.1: 94 percent / TBAF; AcOH / tetrahydrofuran / 0 - 20 °C

6.1: 93 percent / morpholine / Pd(PPh₃)4 / tetrahydrofuran / 72 h / 20 °C

7.1: TFA / CH₂Cl₂ / 20 °C

7.2: 39 percent / N,N-diisopropylethylamine; TBTU / tetrahydrofuran / 20 °C

8.1: 90 percent / H₂ / Pd(OH)2 / methanol / 5.5 h / 20 °C

With morpholine; dmap; lithium hydroxide; diethyl cyanophosphonate; camphor-10-sulfonic acid; tetrabutyl ammonium fluoride; hydrogen; acetic acid; dacarbazine; triethylamine; trifluoroacetic acid; dicyclohexyl(((trifluoromethyl)sulfonyl)oxy)borane; palladium dihydroxide; tetrakis(triphenylphosphine) palladium⁽⁰⁾; In tetrahydrofuran; methanol; hexane; dichloromethane; water; 1.2: aldol reaction;
DOI:10.1016/S0040-4020(03)00110-8