1-Acetyl-6-aminoindoline

Base Information

Chemical Name:1-Acetyl-6-aminoindoline
CAS No.:62368-29-0
Molecular Formula:C10H12N2O
Molecular Weight:176.218
Hs Code.:2933990090
European Community (EC) Number:622-695-5
NSC Number:87623
DSSTox Substance ID:DTXSID00293172
ChEMBL ID:CHEMBL1877102
Mol file:62368-29-0.mol

Synonyms:1-Acetyl-6-aminoindoline;62368-29-0;1-(6-aminoindolin-1-yl)ethanone;1-Acetyl-6-amino-2,3-dihydro-1H-indole;1-(6-amino-2,3-dihydroindol-1-yl)ethanone;1-(6-aminoindolin-1-yl)ethan-1-one;1-acetyl-6-amino-2,3-dihydro-(1h)-indole;1-(6-amino-2,3-dihydro-1H-indol-1-yl)ethan-1-one;MLS002694769;MFCD00056021;1-(6-amino-2,3-dihydro-1H-indol-1-yl)ethanone;NSC87623;1-acetylindolin-6-amine;1-acetyl-6-amino-indoline;NCIOpen2_001034;Oprea1_552062;SCHEMBL399536;CHEMBL1877102;DTXSID00293172;1-Acetyl-6-aminoindoline, powder;LOZKZWIQDVEDCQ-UHFFFAOYSA-N;HMS3087C15;NSC-87623;STK368385;AKOS000224006;PS-4463;SB64214;SMR001560689;1-Acetyl-2,3-dihydro-6-amino-1H-indole;1-acetyl-6-amino-2,3-dihydro(1H)-indole;CS-0046841;FT-0630190;1-(6-Amino-2,3-dihydro-indol-1-yl)ethanone;EN300-112578;1-(6-amino-2,3-dihydro-indol-1-yl)-ethanone;1-Acetyl-6-amino-2 pound not3-dihydro-1H-indole;J-503447;F2189-0315

Suppliers and Price of 1-Acetyl-6-aminoindoline

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

SynQuest Laboratories
1-Acetyl-6-aminoindoline
25 g
$ 549.00

SynQuest Laboratories
1-Acetyl-6-aminoindoline
5 g
$ 149.00

SynQuest Laboratories
1-Acetyl-6-aminoindoline
1 g
$ 76.00

Sigma-Aldrich
1-Acetyl-6-aminoindoline powder
1g
$ 41.10

Matrix Scientific
1-Acetyl-6-amino-2,3-dihydro-(1H)-indole
1g
$ 41.00

Crysdot
1-Acetyl-6-aminoindoline 95+%
25g
$ 473.00

ChemScene
1-(6-Aminoindolin-1-yl)ethan-1-one
5g
$ 245.00

ChemScene
1-(6-Aminoindolin-1-yl)ethan-1-one
1g
$ 82.00

Chemenu
1-(6-aminoindolin-1-yl)ethanone 95%
25g
$ 447.00

Biosynth Carbosynth
1-Acetyl-6-aminoindoline
1 g
$ 60.70

Total 34 raw suppliers

Chemical Property of 1-Acetyl-6-aminoindoline

Chemical Property:

Appearance/Colour:yellow to tan powder
Vapor Pressure:2.11E-08mmHg at 25°C
Melting Point:182 °C
Refractive Index:1.628
Boiling Point:453.2 °C at 760 mmHg
Flash Point:227.9 °C
PSA：46.33000
Density:1.231 g/cm³
LogP:1.82400
Storage Temp.:2-8°C
XLogP3:0.6
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:0
Exact Mass:176.094963011
Heavy Atom Count:13
Complexity:217

Purity/Quality:

97% ^*data from raw suppliers

1-Acetyl-6-aminoindoline ^*data from reagent suppliers

Safty Information:

Pictogram(s): Xn,Xi
Hazard Codes:Xn,Xi
Statements: 22

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

Canonical SMILES:CC(=O)N1CCC2=C1C=C(C=C2)N
Uses Reactant for preparation of:Transient receptor potential cation channel V1 (TRPV1) antagonistsInhibitor of the human immunodeficiency virus (HIV) envelope glycoprotein gp120 binding to the cluster of differentiation 4 (CD4) receptorAntiproliferative agentsSerotonin 5-HT2C/2B receptor antagonists 1-Acetyl-6-aminoindoline is a reactant in the synthesis of anilines, phenols, and heterocycles with aryl iodides.

Technology Process of 1-Acetyl-6-aminoindoline

There total 7 articles about 1-Acetyl-6-aminoindoline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 22949-08-2
1-acetyl-6-nitro-2,3-dihydroindole

: 62368-29-0
1-acetyl-6-aminoindoline

Guidance literature:: With hydrogen; palladium on activated charcoal; In methanol; at 20 ℃; for 1.4h;
DOI:10.1248/cpb.53.1277

Reference yield: 97.0%

: 1-(6-nitro-1H-indol-1-yl)ethan-1-one

: 62368-29-0
1-acetyl-6-aminoindoline

Guidance literature:: With palladium 10% on activated carbon; hydrogen; In methanol; at 20 ℃; for 18h;
DOI:10.1002/ejoc.202101454

Reference yield:

: 496-15-1
1-indoline

: 62368-29-0
1-acetyl-6-aminoindoline

Guidance literature:: Multi-step reaction with 3 steps

1: 80 percent / HNO₃; H₂SO₄ / 20 °C

2: 95 percent / 160 °C

3: 95 percent / H₂ / Pd/C / methanol / 20 °C

With sulfuric acid; hydrogen; nitric acid; palladium on activated charcoal; In methanol;
DOI:10.1016/j.ejmech.2004.10.008