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1-Acetyl-2,3-dihydro-6-nitro-1H-indole is a chemical compound with the molecular formula C11H11N3O3. It is a yellow powder that exhibits potential for use in pharmaceutical and chemical research due to its diverse properties.

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  • 22949-08-2 Structure
  • Basic information

    1. Product Name: 1-Acetyl-2,3-dihydro-6-nitro-1H-indole
    2. Synonyms: 1-Acetyl-2,3-dihydro-6-nitro-1H-indole;1-Acetyl-6-Nitroindole;1-(6-Nitroindolin-1-yl)ethanone;Ethanone, 1-(2,3-dihydro-6-nitro-1H-indol-1-yl)-;1-(6-nitro-1-indolinyl)ethanone;1H-Indole, 1-acetyl-2,3-dihydro-6-nitro-;Indoline, 1-acetyl-6-nitro-;1-(6-Nitroindolin-1-yl)
    3. CAS NO:22949-08-2
    4. Molecular Formula: C10H10N2O3
    5. Molecular Weight: 206.2
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 22949-08-2.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: 450.9 °C at 760 mmHg
    3. Flash Point: 226.5 °C
    4. Appearance: /
    5. Density: 1.35 g/cm3
    6. Vapor Pressure: 2.54E-08mmHg at 25°C
    7. Refractive Index: 1.612
    8. Storage Temp.: Sealed in dry,Room Temperature
    9. Solubility: N/A
    10. CAS DataBase Reference: 1-Acetyl-2,3-dihydro-6-nitro-1H-indole(CAS DataBase Reference)
    11. NIST Chemistry Reference: 1-Acetyl-2,3-dihydro-6-nitro-1H-indole(22949-08-2)
    12. EPA Substance Registry System: 1-Acetyl-2,3-dihydro-6-nitro-1H-indole(22949-08-2)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 22949-08-2(Hazardous Substances Data)

22949-08-2 Usage

Uses

Used in Pharmaceutical Industry:
1-Acetyl-2,3-dihydro-6-nitro-1H-indole is used as an anticancer agent for its ability to inhibit the growth of cancer cells. It has been studied for its potential to target various types of cancer, making it a promising candidate for further research and development in oncology.
1-Acetyl-2,3-dihydro-6-nitro-1H-indole is also used as an anti-inflammatory and analgesic compound, offering potential benefits in the treatment of inflammation and pain management.
Used in Chemical Research:
1-Acetyl-2,3-dihydro-6-nitro-1H-indole is used as a research compound for its antibacterial and antifungal properties, providing insights into the development of new antimicrobial agents.
As a nitro-substituted indole derivative, 1-Acetyl-2,3-dihydro-6-nitro-1H-indole has the potential for further research and development in the pharmaceutical and chemical industries, exploring its applications in various fields.

Check Digit Verification of cas no

The CAS Registry Mumber 22949-08-2 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,2,9,4 and 9 respectively; the second part has 2 digits, 0 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 22949-08:
(7*2)+(6*2)+(5*9)+(4*4)+(3*9)+(2*0)+(1*8)=122
122 % 10 = 2
So 22949-08-2 is a valid CAS Registry Number.
InChI:InChI=1/C10H10N2O3/c1-7(13)11-5-4-8-2-3-9(12(14)15)6-10(8)11/h2-3,6H,4-5H2,1H3

22949-08-2SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 18, 2017

Revision Date: Aug 18, 2017

1.Identification

1.1 GHS Product identifier

Product name 1-(6-nitro-2,3-dihydroindol-1-yl)ethanone

1.2 Other means of identification

Product number -
Other names 1-acetyl-6-nitro-2,3-dihydroindole

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:22949-08-2 SDS

22949-08-2Relevant articles and documents

METHODS FOR TREATING HEPATITIS C

-

Page/Page column 447, (2010/10/20)

In accordance with the present invention, compounds that inhibit viral replication, preferably Hepatitis C Virus (HCV) replication, have been identified, and methods for their use provided. In one aspect of the invention, compounds useful in the treatment

New antiproliferative benzoindolinothiazepines derivatives

Laconde, Guillaume,Depreux, Patrick,Berthelot, Pascal,Pommery, Nicole,Henichart, Jean-Pierre

, p. 167 - 172 (2007/10/03)

New benzoindolinothiazepines containing a piperazine moiety are described as potent antiproliferative agents against PC3 human prostatic cell lines. This activity could be explained by an accumulation of cells in G1 phase.

5H-[1,2,5]selenadiazolo[3,4-f]indole as a masked form of 5,6-diaminoindole

Okwakol, Jealux,Grivas, Spiros

, p. 1939 - 1946 (2007/10/03)

6-Nitroindoline (9) was converted into 1-acetyl-5,6-aminoindoline (12) which was then transformed via selenadiazoles (13-15) to the title selenadiazoloindole (4) by two alternative 3-step synthetic sequences in 38-42% overall yield from 12. The unstable 5,6-diaminoindole (16) was then obtained by reductive deselenation of 4. Fully assigned 1H, 13C and 77Se NMR spectral data for the title indole (4) and 77Se NMR spectral data for the intermediate selenadiazoles (13-15) are presented.

Synthesis of linear tripeptides for right-hand segments of complestatin

Yamada, Yaeko,Akiba, Ai,Arima, Shiho,Okada, Chiharu,Yoshida, Kiminari,Itou, Fumihiro,Kai, Toshitsugu,Satou, Toshiko,Takeda, Kazuyoshi,Harigaya, Yoshihiro

, p. 1277 - 1290 (2007/10/03)

This paper concerns a synthetic study of the right-hand segment of complestatin, an inhibitor of gp120-CD4 receptor. The effective synthesis of four important precursors for the right-hand segment of complestatin is described. Two of them are the precurso

Photo-induced rearrangement of 1-ethoxy-2-phenylindole

Yamada, Koji,Somei, Masanori

, p. 2481 - 2484 (2007/10/03)

Photoirradiation of 1-ethoxy-2-phenylindole in methanol afforded 3- and 6-ethoxy-2-phenylindoles. The structural determination of the latter is carried out by direct comparison of its spectral data with those of the authentic 4-, 5-, 6-, and 7-ethoxy-2-phenylindoles, whose syntheses are also included.

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