4-(2-Carbamoyl-pyrrolidin-1-yl)-4-oxo-butyric acid

Base Information

• Chemical Name: 4-(2-Carbamoyl-pyrrolidin-1-yl)-4-oxo-butyric acid
• CAS No.: 436811-12-0
• Molecular Formula: C9H13N2O4-
• Molecular Weight: 213.2111
• Hs Code.: 2933990090
• DSSTox Substance ID: DTXSID00389827
• Mol file: 436811-12-0.mol

Synonyms:4-(2-Carbamoyl-pyrrolidin-1-yl)-4-oxo-butyric acid;436811-12-0;4-(2-carbamoylpyrrolidin-1-yl)-4-oxobutanoic acid;BAS 03213281;HMS1704N21;Oprea1_215369;Oprea1_671235;DTXSID00389827;VMMYUYRUQLEWTR-UHFFFAOYSA-N;AKOS000300300;AKOS017274662;4-(2-carbamoylpyrrolidin-1-yl)-4-oxobutanoicacid;SR-01000506503;4-(2-carbamoylpyrrolidin-1-yl)-4-oxo-butyric acid;SR-01000506503-1;Butyric acid, 4-(2-carbamoylpyrrolidin-1-yl)-4-oxo-;4-(2-carbamoyl-pyrrolidin-1-yl)-4-oxo-butyric acid, AldrichCPR

Chemical Property of 4-(2-Carbamoyl-pyrrolidin-1-yl)-4-oxo-butyric acid

Chemical Property:

• Vapor Pressure: 4.31E-14mmHg at 25°C
• Boiling Point: 561.7°Cat760mmHg
• Flash Point: 293.5°C
• PSA: 100.70000
• Density: g/cm³
• LogP: -0.03430
• XLogP3: -1.9
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 4
• Exact Mass: 214.09535693
• Heavy Atom Count: 15
• Complexity: 290

Purity/Quality:

98%min ^*data from raw suppliers

4-(2-Carbamoyl-pyrrolidin-1-yl)-4-oxo-butyric acid ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi
• Hazard Codes: Xi

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1CC(N(C1)C(=O)CCC(=O)O)C(=O)N

Technology Process of 4-(2-Carbamoyl-pyrrolidin-1-yl)-4-oxo-butyric acid

There total 1 articles about 4-(2-Carbamoyl-pyrrolidin-1-yl)-4-oxo-butyric acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 38.0%

succinic acid anhydride (108-30-5) + Fmoc-Pro-OH (71989-31-6) → N-succinyl-2S-prolinamide (436811-12-0)

Guidance literature:

Multistep reaction;

DOI:10.1021/jm0500119

upstream raw materials:

succinic acid anhydride

Fmoc-Pro-OH