[(E)-(5-methyl-3,4-dihydro-2H-naphthalen-1-ylidene)amino]urea

Base Information

• Chemical Name: [(E)-(5-methyl-3,4-dihydro-2H-naphthalen-1-ylidene)amino]urea
• CAS No.: 23203-37-4
• Molecular Formula: C₁₂H₁₅N₃O
• Molecular Weight: 217.271
• DSSTox Substance ID: DTXSID80419075
• Mol file: 23203-37-4.mol

Synonyms:NSC115903;DTXSID80419075;23203-37-4

Chemical Property of [(E)-(5-methyl-3,4-dihydro-2H-naphthalen-1-ylidene)amino]urea

Chemical Property:

• Boiling Point: °Cat760mmHg
• Flash Point: °C
• Density: 1.26g/cm³
• XLogP3: 1.6
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 1
• Exact Mass: 217.121512110
• Heavy Atom Count: 16
• Complexity: 301

Purity/Quality:

99% ，98% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC1=C2CCCC(=NNC(=O)N)C2=CC=C1
• Isomeric SMILES: CC1=C2CCC/C(=N\NC(=O)N)/C2=CC=C1

Technology Process of [(E)-(5-methyl-3,4-dihydro-2H-naphthalen-1-ylidene)amino]urea

There total 6 articles about [(E)-(5-methyl-3,4-dihydro-2H-naphthalen-1-ylidene)amino]urea which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

4-(2-carboxy-6-methyl-phenyl)-butyric acid (104665-67-0) → 5-methyl-3,4-dihydro-2H-naphthalen-1-one semicarbazone (23203-37-4)

Guidance literature:

Multi-step reaction with 4 steps

2: sodium; toluene

3: aqueous sulfuric acid

With sulfuric acid; sodium; toluene;

DOI:10.1039/jr9350000997

Reference yield:

4-(2-methylphenyl)butanoic acid (6943-79-9) → 5-methyl-3,4-dihydro-2H-naphthalen-1-one semicarbazone (23203-37-4)

Guidance literature:

Multi-step reaction with 2 steps

1: sulfuric acid

With sulfuric acid;

DOI:10.1039/jr9350000997

Reference yield:

ethyl 5-methyl-1-oxo-1,2,3,4-tetrahydronaphthalene-2-carboxylate → 5-methyl-3,4-dihydro-2H-naphthalen-1-one semicarbazone (23203-37-4)

Guidance literature:

Multi-step reaction with 2 steps

1: aqueous sulfuric acid

With sulfuric acid;

DOI:10.1039/jr9350000997

upstream raw materials:

5-methyl-1-tetralone

4-(2-methylphenyl)butanoic acid

4-(2-carboxy-6-methyl-phenyl)-butyric acid