6943-79-9

Basic information

• Product Name: 4-(2-Methylphenyl)butanoic acid
• Synonyms: 4-(2-Methylphenyl)butanoic acid;Benzenebutanoic acid, 2-Methyl-;4-(o-Tolyl)butanoic acid
• CAS NO: 6943-79-9
• Molecular Formula: C₁₁H₁₄O₂
• Molecular Weight: 178.22766
• EINECS: -0
• Mol File: 6943-79-9.mol
• Article Data: 5

Chemical Properties

• Melting Point: 60 °C
• Boiling Point: 310.9°C at 760 mmHg
• Flash Point: 208°C
• Appearance: /
• Density: 1.072g/cm³
• Vapor Pressure: 0.000251mmHg at 25°C
• Refractive Index: 1.531
• Storage Temp.: 2-8°C
• PKA: 4.76±0.10(Predicted)
• CAS DataBase Reference: 4-(2-Methylphenyl)butanoic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(2-Methylphenyl)butanoic acid(6943-79-9)
• EPA Substance Registry System: 4-(2-Methylphenyl)butanoic acid(6943-79-9)

Safety Data

• Hazardous Substances Data: 6943-79-9(Hazardous Substances Data)

Usage

General Description

4-(2-methylphenyl)butanoic acid, also known as p-methylphenylbutyric acid, is a chemical compound with the molecular formula C11H14O2. It is a derivative of butyric acid and contains a 2-methylphenyl group as a substituent on the butyric acid chain. 4-(2-methylphenyl)butanoic acid is a white crystalline solid with a mild odor and is commonly used in the pharmaceutical industry as a chiral auxiliary in the synthesis of various drugs. It is also known to exhibit anti-inflammatory and analgesic properties, making it useful in the development of new medications for pain relief and inflammation management. Furthermore, 4-(2-methylphenyl)butanoic acid has been studied for its potential as a flavoring agent in the food industry due to its fruity and sweet aroma.

InChI:InChI=1/C11H14O2/c1-9-5-2-3-6-10(9)7-4-8-11(12)13/h2-3,5-6H,4,7-8H2,1H3,(H,12,13)

Upstream product

• 21851-78-5 1-(3-bromopropyl)-2-methylbenzene 
• 1587-04-8 1-methyl-2-(2-propenyl)-benzene 
• 2373-76-4 2-methylcinnamic acid 
• 22084-89-5 3-(2-methylphenyl)propanoic acid 
• 951247-74-8 C₁₁H₁₆O₃S 
• 41010-06-4 4-(o-tolyl)butanenitrile 
• 91193-36-1 4-(4-chloro-2-methylphenyl)-4-oxobutanoic acid 
• 108-41-8 1-chloro-3-methylbenzene 
• 269084-19-7 diethyl 2-[2-(2-methylphenyl)ethyl]propanedioate 
• 39199-37-6 2-(2-methylphenyl)-1-chloroethane 
• 24393-48-4 2-methyl-cinnamic acid ethyl ester 
• 14902-36-4 3-(2-methylphenyl)-1-propanol 
• 36626-29-6 (2-carboxyethyl)triphenylphosphonium chloride 
• 192987-39-6 4-(2-methylphenyl)-3-butenoic acid 

Downstream Products

• 65462-67-1 methyl 4-(o-tolyl)butanoate 
• 81676-04-2 5-(2-methylphenyl)dihydrofuran-2-one 
• 192987-41-0 4-[1-(1-hydroxy-5-methyl-1,2,3,4-tetrahydronaphthyl)]-N-(triphenylmethyl)imidazole 
• 45892-60-2 1-(but-3-en-1-yl)-2-methylbenzene 
• 105986-51-4 ethyl 4-(o-tolyl)butanoate 
• 859809-70-4 4-o-tolyl-butyryl chloride 
• 6939-35-1 5-methyl-1-tetralone 
• 23203-36-3 5-methyl-3,4-dihydro-2H-naphthalen-1-one-(2,4-dinitro-phenylhydrazone) 
• 23203-37-4 5-methyl-3,4-dihydro-2H-naphthalen-1-one semicarbazone 

Relevant articles and documents

Carbonylative Transformation of Allylarenes with CO Surrogates: Tunable Synthesis of 4-Arylbutanoic Acids, 2-Arylbutanoic Acids, and 4-Arylbutanals

In this Communication, procedures for the selective synthesis of 4-arylbutanoic acids, 2-arylbutanoic acids, and 4-arylbutanals from the same allylbenzenes have been developed. With formic acid or TFBen as the CO surrogate, reactions proceed selectively and effectively under carbon monoxide gas-free conditions.

SUBSTITUTED FLUOROETHYL UREAS AS ALPHA 2 ADRENERGIC AGENTS

Therapeutic compounds, and methods, compositions, and medicaments related thereto are disclosed herein.

Hexa-cyclic compound

A novel hexa-cyclic compound, a derivative of camptothecin, of the general formula: STR1 The compound is prepared from an aminoketone compound and a pyranoindolizine compound by the condensation-ring closing reaction. It is abundantly water-soluble, and has an excellent antitumour activity and a high degree of safety, and can be applied as an antitumour medicine for curing tumors of various kinds.