1-phenyloctan-2-ol

Base Information

• Chemical Name: 1-phenyloctan-2-ol
• CAS No.: 19396-72-6
• Molecular Formula: C14H22O
• Molecular Weight: 206.328
• Mol file: 19396-72-6.mol

Synonyms:

Chemical Property of 1-phenyloctan-2-ol

Chemical Property:

• Vapor Pressure: 0.0126mmHg at 25°C
• Boiling Point: 248.8°Cat760mmHg
• Flash Point: 108.8°C
• Density: 0.941g/cm³

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 1-phenyloctan-2-ol

There total 26 articles about 1-phenyloctan-2-ol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

2-Octanone, 1-phenyl- (6683-96-1) → 1-Phenyl-2-octanol (19396-72-6)

Guidance literature:

With sodium tetrahydroborate; In ethanol; water; for 15h; Ambient temperature;

Reference yield: 83.0%

5,5-dimethyl-2-phenyl-1,3,2-dioxaborinane (5123-13-7) + 1,2-Epoxyoctane (2984-50-1) → 1-Phenyl-2-octanol (19396-72-6)

Guidance literature:

With copper(l) iodide; 1,3-diphenylpropanedione; potassium iodide; lithium tert-butoxide; In N,N-dimethyl-formamide; at 80 ℃; for 14h; Reagent/catalyst; Solvent; Temperature; Catalytic behavior; Inert atmosphere; Schlenk technique;

DOI:10.1039/c4cc09321f

Reference yield: 80.0%

1-bromo-hexane (111-25-1) + 2,2'‐(2‐phenylethane‐1,1‐diyl)bis(4,4,5,5‐tetramethyl‐1,3,2‐dioxaborolane) (1151549-62-0) → 1-Phenyl-2-octanol (19396-72-6)

Guidance literature:

1-bromo-hexane; 2,2'‐(2‐phenylethane‐1,1‐diyl)bis(4,4,5,5‐tetramethyl‐1,3,2‐dioxaborolane); With sodium methylate; In tetrahydrofuran; at 25 ℃; for 16h; Inert atmosphere; Schlenk technique;

With dihydrogen peroxide; sodium hydroxide; In water; at 0 - 25 ℃; for 3h;

DOI:10.1002/anie.202002642

upstream raw materials:

heptanal

benzylmagnesium chloride

styrene oxide

1-hexene

Downstream raw materials:

heptanal

2-Octanone, 1-phenyl-