5123-13-7 Usage
Description
(5,5-DIMETHYL-1,3,2-DIOXABORINAN-2-YL)BENZENE is a chemical compound that features a benzene ring fused to a boron-containing five-membered ring. This unique structure endows it with the capability to form robust covalent bonds with other molecules, which is highly beneficial in the synthesis of complex organic compounds. Its applications are primarily in the realms of pharmaceuticals and agrochemicals, where it serves as a versatile building block. Moreover, it has garnered interest in materials science and catalysis due to its potential to enhance the properties of various materials and chemical reactions. However, the presence of boron necessitates careful handling and adherence to safety protocols to mitigate any health or environmental hazards.
Uses
Used in Pharmaceutical Industry:
(5,5-DIMETHYL-1,3,2-DIOXABORINAN-2-YL)BENZENE is used as a key intermediate in the synthesis of pharmaceuticals for its ability to form stable covalent bonds with biologically active molecules, contributing to the development of new drugs with enhanced efficacy and selectivity.
Used in Agrochemical Industry:
In the agrochemical sector, (5,5-DIMETHYL-1,3,2-DIOXABORINAN-2-YL)BENZENE is utilized as a building block in the creation of novel agrochemicals, such as pesticides and herbicides, where its strong bonding capabilities can improve the performance and selectivity of these compounds towards target organisms.
Used in Materials Science:
(5,5-DIMETHYL-1,3,2-DIOXABORINAN-2-YL)BENZENE is employed in materials science as a component in the design of advanced materials, leveraging its bonding properties to enhance the mechanical, thermal, or electrical properties of the resulting materials.
Used in Catalysis:
In the field of catalysis, (5,5-DIMETHYL-1,3,2-DIOXABORINAN-2-YL)BENZENE is used to modify catalysts, potentially improving their activity, selectivity, and stability by forming strong bonds with reaction intermediates or by stabilizing catalytically active species.
Check Digit Verification of cas no
The CAS Registry Mumber 5123-13-7 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 5,1,2 and 3 respectively; the second part has 2 digits, 1 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 5123-13:
(6*5)+(5*1)+(4*2)+(3*3)+(2*1)+(1*3)=57
57 % 10 = 7
So 5123-13-7 is a valid CAS Registry Number.
InChI:InChI=1/C11H15BO2/c1-11(2)8-13-12(14-9-11)10-6-4-3-5-7-10/h3-7H,8-9H2,1-2H3
5123-13-7Relevant articles and documents
Photochemical and electrochemical C-N borylation of arylhydrazines
Du, Linlin,Sun, Li,Zhang, Hua
supporting information, p. 1716 - 1719 (2022/02/21)
The C-N borylation of arylhydrazine hydrochlorides with bis(pinacolato)diboron was achieved under photochemical and electrochemical conditions, respectively. This novel and scalable transformation provides two efficient and mild transition-metal-free synt
Cobalt-Catalyzed C(sp2)-C(sp3) Suzuki-Miyaura Cross Coupling
Ludwig, Jacob R.,Simmons, Eric M.,Wisniewski, Steven R.,Chirik, Paul J.
supporting information, (2020/11/02)
A cobalt-catalyzed method for the C(sp2)-C(sp3) Suzuki-Miyaura cross coupling of aryl boronic esters and alkyl bromides is described. Cobalt-ligand combinations were assayed with high-throughput experimentation, and cobalt(II) sources with trans-N,N′-dimethylcyclohexane-1,2-diamine (DMCyDA, L1) produced optimal yield and selectivity. The scope of this transformation encompassed steric and electronic diversity on the aryl boronate nucleophile as well as various levels of branching and synthetically valuable functionality on the electrophile. Radical trap experiments support the formation of electrophile-derived radicals during catalysis.
Synthesis of arylboronates via the Pd-catalyzed desulfitative coupling reaction of sodium arylsulfinates with bis(pinacolato)diboron
Qiu, Di,Li, Songyi,Yue, Guanglu,Mao, Jinshan,Xu, Bei,Yuan, Xinyu,Ye, Fei
, (2021/11/04)
The desulfitative borylation reaction of sodium arylsulfinates with bis(pinacolato)diboron or bis(neopentylglycolato)diboron under palladium catalysis has been developed, allowing selective C-B bond formation to give arylboronates with a range of functional groups in moderate to good yields under mild reaction conditions. A gram-scale preparation as well as the cascade Suzuki-Miyaura cross-coupling of arylboronates demonstrated the potential practical utility in organic synthesis.
