(S)-2-amino-5-[(aminocarbonyl)amino]-N-(4-nitrophenyl)valeramide monohydrobromide

Base Information

• Chemical Name: (S)-2-amino-5-[(aminocarbonyl)amino]-N-(4-nitrophenyl)valeramide monohydrobromide
• CAS No.: 83575-39-7
• Molecular Formula: C12H17 N5 O4 . Br H
• Molecular Weight: 376.21
• Hs Code.: 2924299090
• Mol file: 83575-39-7.mol

Synonyms:(S)-2-amino-5-[(aminocarbonyl)amino]-N-(4-nitrophenyl)valeramide monohydrobromide

Chemical Property of (S)-2-amino-5-[(aminocarbonyl)amino]-N-(4-nitrophenyl)valeramide monohydrobromide

Chemical Property:

• Vapor Pressure: 6E-14mmHg at 25°C
• Boiling Point: 591.1°C at 760 mmHg
• Flash Point: 311.3°C
• PSA: 157.05000
• LogP: 3.46840

Purity/Quality:

99% ^*data from raw suppliers

L-CITRULLINE-PARA-NITROANILIDE HYDROBROMIDE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of (S)-2-amino-5-[(aminocarbonyl)amino]-N-(4-nitrophenyl)valeramide monohydrobromide

There total 1 articles about (S)-2-amino-5-[(aminocarbonyl)amino]-N-(4-nitrophenyl)valeramide monohydrobromide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

Nα-benzyloxycarbonyl-L-citrulline p-nitroanilide (83575-37-5) → L-citrulline p-nitroanilide hydrobromide (83575-39-7)

Guidance literature:

With hydrogen bromide; In acetic acid; for 1.5h; Yield given; Ambient temperature;

DOI:10.1016/0040-4020(82)80232-9

Reference yield: 85.0%

L-citrulline p-nitroanilide hydrobromide (83575-39-7) + p-toluenesulfonyl chloride (98-59-9) → Nα-tosyl-L-citrulline p-nitroanilide (83575-40-0)

Guidance literature:

With triethylamine; In N,N-dimethyl-formamide; 1.) cooling, 5 min., 2.) room temp., 15 min.;

DOI:10.1016/0040-4020(82)80232-9

Reference yield: 61.0%

N-benzyloxycarbonyl-L-phenylalanine p-nitrophenyl ester (2578-84-9) + L-citrulline p-nitroanilide hydrobromide (83575-39-7) → benzyloxycarbonyl-L-phenylalanyl-L-citrulline p-nitroanilide (83590-79-8)

Guidance literature:

With triethylamine; In N,N-dimethyl-formamide; for 18h; Ambient temperature;

DOI:10.1016/0040-4020(82)80232-9

upstream raw materials:

Nα-benzyloxycarbonyl-L-citrulline p-nitroanilide

Downstream raw materials:

benxyloxycarbonylglycyl-L-citrulline p-nitroanilide

benzyloxycarbonylglycyl-L-phenylalanyl-L-citrulline p-nitroanilide

benzyloxycarbonyl-L-phenylalanyl-L-citrulline p-nitroanilide

Nα-acetyl-L-citrulline p-nitroanilide