Benzyloxycarbonylglycyl-phenylalanyl-citrulline 4-nitroanilide

Base Information

Chemical Name:Benzyloxycarbonylglycyl-phenylalanyl-citrulline 4-nitroanilide
CAS No.:83575-50-2
Molecular Formula:C₃₁H₃₅N₇O₈
Molecular Weight:633.661
Hs Code.:
Mol file:83575-50-2.mol

Synonyms:(Benzyloxycarbonyl)glycylphenylalanylcitrullinenitroanilide

Suppliers and Price of Benzyloxycarbonylglycyl-phenylalanyl-citrulline 4-nitroanilide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Chemicals and raw materials
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Total 3 raw suppliers

Chemical Property of Benzyloxycarbonylglycyl-phenylalanyl-citrulline 4-nitroanilide

Chemical Property:

Vapor Pressure:0mmHg at 25°C
Melting Point:167 - 170 °C (ethyl acetate)
Boiling Point:948.1°C at 760 mmHg
Flash Point:527.2°C
PSA：226.57000
Density:1.342g/cm³
LogP:4.98060

Purity/Quality:

Safty Information:

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Hazard Codes:

MSDS Files:

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Technology Process of Benzyloxycarbonylglycyl-phenylalanyl-citrulline 4-nitroanilide

There total 2 articles about Benzyloxycarbonylglycyl-phenylalanyl-citrulline 4-nitroanilide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 83575-37-5
Nα-benzyloxycarbonyl-L-citrulline p-nitroanilide

: 83575-50-2
benzyloxycarbonylglycyl-L-phenylalanyl-L-citrulline p-nitroanilide

Guidance literature:: Multi-step reaction with 2 steps

1: HBr in HOAc / acetic acid / 1.5 h / Ambient temperature

2: 1.) N-methylmorpholine, 1-hydroxybenzotriazole, 2.) dicyclohexylcarbodiimide / 2.) DMF, -5 deg C, 45 min., 3.) room temp., 20 h

With 4-methyl-morpholine; hydrogen bromide; benzotriazol-1-ol; dicyclohexyl-carbodiimide; In acetic acid;
DOI:10.1016/0040-4020(82)80232-9

Reference yield:

: 1170-76-9
Z-Gly-(L)-Phe

: 83575-39-7
L-citrulline p-nitroanilide hydrobromide

: 83575-50-2
benzyloxycarbonylglycyl-L-phenylalanyl-L-citrulline p-nitroanilide

Guidance literature:: With 4-methyl-morpholine; benzotriazol-1-ol; dicyclohexyl-carbodiimide; Yield given. Multistep reaction; 2.) DMF, -5 deg C, 45 min., 3.) room temp., 20 h;
DOI:10.1016/0040-4020(82)80232-9