3-(pyridin-4-yl)-1,2,4-oxadiazol-5(2H)-one

Base Information

Chemical Name:3-(pyridin-4-yl)-1,2,4-oxadiazol-5(2H)-one
CAS No.:102227-52-1
Molecular Formula:C₇H₅N₃O₂
Molecular Weight:163.136
Hs Code.:
Mol file:102227-52-1.mol

Synonyms:3-(4-Pyridinyl)-1,2,4-oxadiazol-5(2H)-one;4-(5-Hydroxy-1,2,4-oxadiazol-3-yl)pyridine

Suppliers and Price of 3-(pyridin-4-yl)-1,2,4-oxadiazol-5(2H)-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of 3-(pyridin-4-yl)-1,2,4-oxadiazol-5(2H)-one

Chemical Property:

Vapor Pressure:0.00793mmHg at 25°C
Boiling Point:267.9°Cat760mmHg
Flash Point:115.8°C
Density:1.53g/cm³

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 3-(pyridin-4-yl)-1,2,4-oxadiazol-5(2H)-one

There total 5 articles about 3-(pyridin-4-yl)-1,2,4-oxadiazol-5(2H)-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 55.0%

: 1594-57-6,849833-58-5
pyridine-4-carboxamidoxime

: 541-41-3
chloroformic acid ethyl ester

: 102227-52-1
3-(pyridin-4-yl)-4H-[1,2,4]oxadiazol-5-one

Guidance literature:: With pyridine; for 6h; Reflux;
DOI:10.1002/jhet.251

Reference yield: 26.0%

: 463-72-9
carbamic chloride

: 1594-57-6,849833-58-5
pyridine-4-carboxamidoxime

: 102227-52-1
3-(pyridin-4-yl)-4H-[1,2,4]oxadiazol-5-one

Guidance literature:: With pyridine; for 3h; Reflux;
DOI:10.1002/jhet.251

Reference yield:

: 100-48-1
pyridine-4-carbonitrile

: 102227-52-1
3-(pyridin-4-yl)-4H-[1,2,4]oxadiazol-5-one

Guidance literature:: Multi-step reaction with 3 steps

1: 90 percent / aq. NH₂OH*HCl; Na₂CO₃ / ethanol / 70 °C

2: pyridine / dimethylformamide / 3 h / 0 - 20 °C

3: toluene / 24 h / Heating

With pyridine; hydroxylamine hydrochloride; sodium carbonate; In ethanol; N,N-dimethyl-formamide; toluene;
DOI:10.1021/jm000350w