2-Amino-5-iodobenzamide

Base Information

• Chemical Name: 2-Amino-5-iodobenzamide
• CAS No.: 32658-67-6
• Molecular Formula: C7H7IN2O
• Molecular Weight: 262.05
• DSSTox Substance ID: DTXSID80186331
• Wikidata: Q83057590
• Mol file: 32658-67-6.mol

Synonyms:2-Amino-5-iodobenzamide;32658-67-6;Benzamide, 2-amino-5-iodo-;BRN 2831469;C7H7IN2O;5-iodoanthranilic acid amide;SCHEMBL688910;DTXSID80186331;C7-H7-I-N2-O;LS-25560;BB 0257175;CS-0380035;FT-0696104;F83954

Chemical Property of 2-Amino-5-iodobenzamide

Chemical Property:

• Vapor Pressure: 0.000203mmHg at 25°C
• Melting Point: 197-198 °C(Solv: water (7732-18-5); methanol (67-56-1))
• Boiling Point: 327.4°Cat760mmHg
• PKA: 15.21±0.50(Predicted)
• Flash Point: 151.8°C
• PSA: 70.10000
• Density: 1.977g/cm³
• LogP: 2.43770
• XLogP3: 1.4
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 1
• Exact Mass: 261.96031
• Heavy Atom Count: 11
• Complexity: 163

Purity/Quality:

99% ^*data from raw suppliers

2-Amino-5-iodobenzamide 95+% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC(=C(C=C1I)C(=O)N)N

Technology Process of 2-Amino-5-iodobenzamide

There total 10 articles about 2-Amino-5-iodobenzamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

5-iodoisatoic anhydride (116027-10-2) → 2-amino-5-iodoanthranilamide (32658-67-6)

Guidance literature:

With ammonia; In DMF (N,N-dimethyl-formamide); water;

Reference yield: 95.0%

anthranilic acid amide (28144-70-9,88-68-6) → 2-amino-5-iodoanthranilamide (32658-67-6)

Guidance literature:

With iodine; sodium hydrogencarbonate; In water; at 20 ℃;

DOI:10.1016/j.ejmech.2013.04.068

Reference yield: 89.0%

(2-amino-5-iodophenyl) (benzotriazole-1-yl)methanone (1397833-74-7) → 2-amino-5-iodoanthranilamide (32658-67-6)

Guidance literature:

With ammonium hydroxide; In tetrahydrofuran; water; at 0 ℃; for 2h;

DOI:10.3998/ark.5550190.0013.818

upstream raw materials:

5-iodoisatoic anhydride

2-amino-5-iodobenzoic acid

bis(trichloromethyl) carbonate

anthranilic acid amide

Downstream raw materials:

2-(2,4-dihydroxy-phenyl)-6-iodo-3H-quinazolin-4-one

2-amino-5-(4-pyridinyl)benzamide

2-amino-3-bromo-5-(4-pyridinyl)benzamide

pentafluorophenyl 6'-amino-5'-(aminocarbonyl)-1,1':3',1''-terphenyl-4-sulfonate