4-Fluorothreonine

Base Information

Chemical Name:4-Fluorothreonine
CAS No.:102130-93-8
Molecular Formula:C₄H₈FNO₃
Molecular Weight:137.111
Hs Code.:
DSSTox Substance ID:DTXSID80144678
Nikkaji Number:J663.929A
Wikipedia:4-Fluoro-L-threonine
Wikidata:Q18349175
Metabolomics Workbench ID:53586
Mol file:102130-93-8.mol

Synonyms:4-fluorothreonine

Suppliers and Price of 4-Fluorothreonine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
(2S,3S)-2-AMINO-4-FLUORO-3-HYDROXYBUTANOIC ACID 95.00%
5MG
$ 496.68

Total 8 raw suppliers

Chemical Property of 4-Fluorothreonine

Chemical Property:

Vapor Pressure:1.18E-07mmHg at 25°C
Boiling Point:388.9°Cat760mmHg
Flash Point:189°C
PSA：83.55000
Density:1.419g/cm³
LogP:-0.57100
XLogP3:-3
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:3
Exact Mass:137.04882128
Heavy Atom Count:9
Complexity:108

Purity/Quality:

97% ^*data from raw suppliers

(2S,3S)-2-AMINO-4-FLUORO-3-HYDROXYBUTANOIC ACID 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C(C(C(C(=O)O)N)O)F
Isomeric SMILES:C([C@H]([C@@H](C(=O)O)N)O)F

Technology Process of 4-Fluorothreonine

There total 8 articles about 4-Fluorothreonine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 64.0%

: 194666-37-0
Benzoic acid (S)-1-((2R,4S)-2-tert-butyl-1-methyl-5-oxo-imidazolidin-4-yl)-2-fluoro-ethyl ester

: 89426-34-6,102130-93-8
4-fluoro-L-threonine

Guidance literature:: With hydrogenchloride; at 100 ℃; for 72h;
DOI:10.1039/a703121a

Reference yield:

: 731-98-6
5’-fluoro-5’-deoxyadenosine

: 371-62-0
2-fluoroethanol

: 144-49-0
Fluoroacetic acid

: 89426-34-6,102130-93-8
4-fluoro-L-threonine

: 5'-fluoro-5'-deoxyinosine

Guidance literature:: With Streptomyces cattleya NRRL 8057; Tris buffer; sodium fluoride; at 28 ℃; for 20h; pH=7.8; Further byproducts given;
DOI:10.1002/1521-3773(20021018)41:20<3913::AID-ANIE3913>3.0.CO;2-E

Reference yield:

: 14031-35-7,17176-17-9,29908-03-0,75044-81-4,78548-84-2,79647-17-9,91279-78-6
S-Adenosyl-L-methionine

: 144-49-0
Fluoroacetic acid

: 89426-34-6,102130-93-8
4-fluoro-L-threonine

Guidance literature:: With Streptomyces cattleya NRRL 8057; Tris buffer; sodium fluoride; at 28 ℃; for 20h; pH=7.8;
DOI:10.1002/1521-3773(20021018)41:20<3913::AID-ANIE3913>3.0.CO;2-E