ethyl [(methylsulfonyl)oxy]acetate

Base Information

• Chemical Name: ethyl [(methylsulfonyl)oxy]acetate
• CAS No.: 29169-19-5
• Molecular Formula: C5H10 O5 S
• Molecular Weight: 182.197
• Mol file: 29169-19-5.mol

Synonyms:Aceticacid, [(methylsulfonyl)oxy]-, ethyl ester (9CI); Glycolic acid, ethyl ester,methanesulfonate (6CI,8CI); Carbethoxymethyl methanesulfonate; NSC 24898

Chemical Property of ethyl [(methylsulfonyl)oxy]acetate

Chemical Property:

• Vapor Pressure: 0.00119mmHg at 25°C
• Boiling Point: 299.4°C at 760 mmHg
• Flash Point: 134.9°C
• Density: 1.283g/cm³

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of ethyl [(methylsulfonyl)oxy]acetate

There total 3 articles about ethyl [(methylsulfonyl)oxy]acetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

ethyl 2-hydroxyacetate (623-50-7) + methanesulfonyl chloride (124-63-0) → ethyl α-methanesulfonyloxyacetate (29169-19-5)

Guidance literature:

With triethylamine; In ethyl acetate; at 0 - 20 ℃; for 1h;

Reference yield:

ethyl iodoacetae (623-48-3) → ethyl α-methanesulfonyloxyacetate (29169-19-5)

Guidance literature:

With acetonitrile;

DOI:10.1139/v56-099

Reference yield:

→ ethyl α-methanesulfonyloxyacetate (29169-19-5)

Guidance literature:

upstream raw materials:

ethyl 2-hydroxyacetate

methanesulfonyl chloride

ethyl iodoacetae

Downstream raw materials:

α-(trifluoromethoxy)ethyl acetate

ethyl-2-azidoacetate