1-(2,3-Epoxypropoxy)-2,2-bis[(2,3-epoxypropoxy)methyl]butane

Base Information

• Chemical Name: 1-(2,3-Epoxypropoxy)-2,2-bis[(2,3-epoxypropoxy)methyl]butane
• CAS No.: 3454-29-3
• Deprecated CAS: 1149843-23-1,153355-08-9
• Molecular Formula: C15H26 O6
• Molecular Weight: 302.368
• European Community (EC) Number: 222-384-0,608-489-8
• DSSTox Substance ID: DTXSID90873907
• Nikkaji Number: J216.129J
• Wikipedia: Trimethylolpropane_triglycidyl_ether
• Mol file: 3454-29-3.mol

Synonyms:Trimethylolpropane triglycidyl ether;3454-29-3;30499-70-8;1-(2,3-EPOXYPROPOXY)-2,2-BIS[(2,3-EPOXYPROPOXY)METHYL]BUTANE;EINECS 222-384-0;2-[2,2-bis(oxiran-2-ylmethoxymethyl)butoxymethyl]oxirane;DTXSID90873907;2,2'-(((2-Ethyl-2-((oxiran-2-ylmethoxy)methyl)propane-1,3-diyl)bis(oxy))bis(methylene))bis(oxirane);1-(2,3-Epoxypropoxy)-2,2-bis((2,3-epoxypropoxy)methyl)butane;Oxirane, 2,2'-((2-ethyl-2-((oxiranylmethoxy)methyl)-1,3-propanediyl)bis(oxymethylene))bis-;Oxirane, 2,2'-[[2-ethyl-2-[(oxiranylmethoxy)methyl]-1,3-propanediyl]bis(oxymethylene)]bis-;SCHEMBL36668;CHEBI:189372;BCP30301;MFCD00274208;1,1,1-Tris(glycidyloxymethyl)propane;AKOS015912442;(C6-H14-O3.C3-H5-Cl-O)x-;1,1,1-trimethylolpropane triglycidyl ether;LS-183891;FT-0688198;EC 608-489-8;A852258;Trimethylolpropane triglycidyl ether, technical grade;W-109898;2-({2,2-Bis[(2-oxiranylmethoxy)methyl]butoxy}methyl)oxirane;2-((2,2-bis(((oxiran-2-yl)methoxy)methyl)butoxy)methyl)oxirane;2,2'-(2-ethyl-2-((oxiran-2-ylmethoxy)methyl)propane-1,3-diyl)bis(oxy)bis(methylene)dioxirane

Chemical Property of 1-(2,3-Epoxypropoxy)-2,2-bis[(2,3-epoxypropoxy)methyl]butane

Chemical Property:

• Refractive Index: n20/D 1.477(lit.)
• Boiling Point: 410.7°Cat760mmHg
• Flash Point: 167.9°C
• PSA: 65.28000
• Density: 1.175g/cm³
• LogP: 0.62900
• Storage Temp.: Refrigerator
• Solubility.: Chloroform (Sparingly), Methanol (Slightly)
• XLogP3: -0.1
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 6
• Rotatable Bond Count: 13
• Exact Mass: 302.17293854
• Heavy Atom Count: 21
• Complexity: 278

Purity/Quality:

98%,99%, ^*data from raw suppliers

Trimethylolpropane triglycidyl ether technical grade ^*data from reagent suppliers

Safty Information:

• Hazard Codes: Xi
• Statements: 36/37/38-41-43
• Safety Statements: 26-36/37

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Canonical SMILES: CCC(COCC1CO1)(COCC2CO2)COCC3CO3
• Uses: Trimethylolpropane Triglycidyl Ether is used in method for producing pharmaceutical filler complex.

Technology Process of 1-(2,3-Epoxypropoxy)-2,2-bis[(2,3-epoxypropoxy)methyl]butane

There total 4 articles about 1-(2,3-Epoxypropoxy)-2,2-bis[(2,3-epoxypropoxy)methyl]butane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

trimethylolpropane triallyl ether (682-08-6) → 1,1,1-trimethylolpropane triglycidyl ether (3454-29-3,42765-17-3)

Guidance literature:

With 3-chloro-benzenecarboperoxoic acid; In chloroform; at 20 ℃; for 72h;

Reference yield: 76.0%

1,1,1-tri(hydroxymethyl)propane (77-99-6) + epichlorohydrin (106-89-8,24969-06-0,13403-37-7) → 1,1,1-trimethylolpropane triglycidyl ether (3454-29-3,42765-17-3)

Guidance literature:

With potassium hydroxide; In dimethyl sulfoxide; at 30 ℃; for 7h;

DOI:10.1055/s-1993-25890

Reference yield:

1,1,1-tri(hydroxymethyl)propane (77-99-6) → 1,1,1-trimethylolpropane triglycidyl ether (3454-29-3,42765-17-3)

Guidance literature:

Multi-step reaction with 2 steps

1: potassium hydroxide; tetrabutylammomium bromide / tetrahydrofuran / 24 h / 70 °C

2: 3-chloro-benzenecarboperoxoic acid / chloroform / 72 h / 20 °C

With tetrabutylammomium bromide; 3-chloro-benzenecarboperoxoic acid; potassium hydroxide; In tetrahydrofuran; chloroform;

upstream raw materials:

1,1,1-tri(hydroxymethyl)propane

epichlorohydrin

trimethylolpropane triallyl ether

Downstream raw materials:

C₅₇H₇₁N₃O₆