2,3-Dichlorothiophene

Base Information

• Chemical Name: 2,3-Dichlorothiophene
• CAS No.: 17249-79-5
• Molecular Formula: C4H2Cl2S
• Molecular Weight: 153.032
• Hs Code.: 29349990
• Mol file: 17249-79-5.mol

Synonyms:2,3-Dichlorthiophen;

Chemical Property of 2,3-Dichlorothiophene

Chemical Property:

• Appearance/Colour: Colorless to light yellow liquid
• Vapor Pressure: 1.93mmHg at 25°C
• Melting Point: -26 °C
• Refractive Index: n20/D 1.5680(lit.)
• Boiling Point: 170.708 °C at 760 mmHg
• Flash Point: 68.916 °C
• PSA: 28.24000
• Density: 1.488 g/cm³
• LogP: 3.05490
• Storage Temp.: 2-8°C

Purity/Quality:

98%,99%, ^*data from raw suppliers

2,3-Dichlorothiophene ^*data from reagent suppliers

Safty Information:

• Pictogram(s): T
• Hazard Codes: T
• Statements: 25-43
• Safety Statements: 26-36/37/39-45

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Uses: Reactant for:Synthesis of enediyne-chlorophyll derivatives as antitumor cytotoxic conjugatesSelective electrochemical mono- and polysilylation

Technology Process of 2,3-Dichlorothiophene

There total 7 articles about 2,3-Dichlorothiophene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 8.0%

3-chlorothiophene (17249-80-8) → 2,3-Dichlorothiophene (17249-79-5) + 2,3,5-trichlorothiophene (17249-77-3)

Guidance literature:

With chlorine; In tetrachloromethane; at 0 ℃; for 0.75h;

Reference yield:

2,3,4,5-tetrachloro-tetrahydro-thiophene (64048-11-9) → 2,4-dichlorothiophene (17249-75-1) + 2,5-diclorothiophene (3172-52-9,173777-89-4) + 2,3-Dichlorothiophene (17249-79-5)

Guidance literature:

optically inactive stereoisomer(ic) of mp: 113 degree; Erhitzen auf 180grad;

DOI:10.1021/ja01183a083

Reference yield:

4,5-dichlorothiophene-2-carboxylic acid (31166-29-7) → 2,3-Dichlorothiophene (17249-79-5)

Guidance literature:

With mercury(II) diacetate; acetic acid; anschliessend behandeln mit Natriumchlorid in Wasser und mit wss. Salzsaeure;

upstream raw materials:

4,5-dichlorothiophene-2-carboxylic acid

2,3,4,5-tetrachloro-tetrahydro-thiophene

3-chlorothiophene

2,4-dichlorothiophene

Downstream raw materials:

1-(4,5-Dichlor-2-thienyl)-ethanon

Acenaphtho<1,2-b>thiophene

4,5-dichlorothiophene-2-carboxylic acid

(4,5-Dichloro-thiophen-2-yl)-oxo-acetic acid ethyl ester

Refernces

• 1、 Dettmeier, Udo,Eichler, Klaus,Kuehlein, Klaus,Leupold, Ernst Ingo,Litterer, Heinz. "Herstellung von β-Halogenthiophenen durch Isomerisierung von α-Halogenthiophenen an Zeolithkatalysatoren". . p. 470 - 471. Retrieved 2007/10/02.