Mukeic acid

Base Information

Chemical Name:Mukeic acid
CAS No.:3889-89-2
Molecular Formula:C14H11NO3
Molecular Weight:0
Hs Code.:
Mol file:3889-89-2.mol

Synonyms:Mukeic acid;1-Hydroxy-9H-carbazole-3-carboxylic acid;CHEBI:169663;54279-86-6

Suppliers and Price of Mukeic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 3 raw suppliers

Chemical Property of Mukeic acid

Chemical Property:

PSA：62.32000
LogP:3.02790
XLogP3:2.6
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:1
Exact Mass:227.058243149
Heavy Atom Count:17
Complexity:320

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C2C(=C1)C3=C(N2)C(=CC(=C3)C(=O)O)O

Technology Process of Mukeic acid

There total 11 articles about Mukeic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

: 23523-94-6
1-methoxy-3-methoxycarbonyl-9H-carbazole

: 3889-89-2
mukoeic acid

Guidance literature:: With potassium hydroxide; In ethanol; for 5h; Reflux;
DOI:10.1016/j.tetlet.2016.01.002

Reference yield: 92.0%

: 182261-83-2
methyl 1-hydroxy-9H-carbazole-3-carboxylate

: 3889-89-2
mukoeic acid

Guidance literature:: With sodium hydroxide; In ethanol; at 50 ℃; for 1h;
DOI:10.1016/S0040-4020(97)10366-0

Reference yield:

: 175153-75-0
3-methoxy-4-trifluoromethane-sulfonyloxy-benzoic acid methyl ester

: 3889-89-2
mukoeic acid

Guidance literature:: Multi-step reaction with 3 steps

1: tris-(dibenzylideneacetone)dipalladium⁽⁰⁾; 2,2'-bis-(diphenylphosphino)-1,1'-binaphthyl; caesium carbonate / toluene / 8 h / Inert atmosphere; Sealed tube; Reflux

2: palladium diacetate; 1,3-bis(2,4,6-trimethylphenyl)-4,5-dihydroimidazolium chloride; potassium carbonate / N,N-dimethyl acetamide / 10 h / 150 °C / Inert atmosphere; Sealed tube

3: sodium hydroxide / methanol / 5 h / Inert atmosphere; Sealed tube; Reflux

With tris-(dibenzylideneacetone)dipalladium⁽⁰⁾; palladium diacetate; potassium carbonate; caesium carbonate; 2,2'-bis-(diphenylphosphino)-1,1'-binaphthyl; 1,3-bis(2,4,6-trimethylphenyl)-4,5-dihydroimidazolium chloride; sodium hydroxide; In methanol; N,N-dimethyl acetamide; toluene;
DOI:10.1002/cjoc.201800149